The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: A single-center experience

Jamila Kremer, Mina Farag, Marcin Zaradzki, G. Szabó, Arjang Ruhparwar, Klaus Kallenbach, Matthias Karck, Rawa Arif

Research output: Contribution to journalArticle

Abstract

Valve-sparing aortic root replacement (VSARR) through reimplantation technique is widely regarded as optimal surgical approach for Marfan syndrome (MFS) patients. Perioperative and long-term data from all MFS patients undergoing VSARR using David’s technique at our center from 2007–2018 were analyzed. We included 56 patients with a mean age of 32.3 ± 12.3 years. Logistic EuroSCORE was 7.96 ± 5.2. Among others concomitant surgical procedures included aortic arch surgery (8.9%), mitral valve repair (23.2%) and replacement (1.7%). There were no operative deaths, nor in-hospital-mortality. One patient underwent re-exploration for bleeding, dialysis and pacemaker implantation was required in one case each. There was no occurrence of low-output syndrome nor neurological complications. Significant gender differences were not found, except for intraoperative blood transfusion occurring significantly more often in the female gender (p = 0.009). Despite significantly longer procedural times, concomitant surgery did not negatively impact overall outcome. Freedom of reoperation of the aortic root was 100% at 1 year, 97.7% at 8 years. Until last follow-up (61 ± 38 month) all patients survived, with no evidence of endocarditis. We emphasize once more that VSARR using David’s procedure is a safe method for MFS patients with excellent long-term results even if concomitant procedures are performed.

Original languageEnglish
Article number12021
JournalScientific reports
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 1 2019

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Marfan Syndrome
Replantation
Aortic Valve
Hospital Mortality
Endocarditis
Thoracic Aorta
Mitral Valve
Reoperation
Blood Transfusion
Dialysis
Hemorrhage

ASJC Scopus subject areas

  • General

Cite this

The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome : A single-center experience. / Kremer, Jamila; Farag, Mina; Zaradzki, Marcin; Szabó, G.; Ruhparwar, Arjang; Kallenbach, Klaus; Karck, Matthias; Arif, Rawa.

In: Scientific reports, Vol. 9, No. 1, 12021, 01.12.2019.

Research output: Contribution to journalArticle

Kremer, Jamila ; Farag, Mina ; Zaradzki, Marcin ; Szabó, G. ; Ruhparwar, Arjang ; Kallenbach, Klaus ; Karck, Matthias ; Arif, Rawa. / The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome : A single-center experience. In: Scientific reports. 2019 ; Vol. 9, No. 1.
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