Foszfolipid-ellenes antitestek elo″fordulása fiatal no″kben kombinált orális fogamzásgátló szedése mellett

Translated title of the contribution: The presence of antiphospholipid antibodies in young women during use of oral contraceptives

Vad Szilvia, Lakos Gabriella, E. Kiss, Peto Erika, Póka Róbert

Research output: Contribution to journalArticle

Abstract

The role of thrombophilia in the elevated risk of thromboembolism during oral contraceptive (OC) use has been established. The most common form of acquired thrombophilia is the presence of antiphospholipid antibodies in the blood. We performed a cross-sectional study among young women to survey the occurrence of antiphospholipid antibodies among users and non-users of OC. Serum levels of IgG, IgA and IgM isotypes of anti-2-glycoprotein I and anticardiolipin antibodies were measured by validated ELISA methods. Regardless of the type of antiphospholipid antibody, pill-users had an elevated antibody titer more than twice as frequently as non-users (OR=2.3, 95%CI 1.1-5.1). The higher frequency of elevated antibody titer was related most commonly to IgG type anti-2-glyco-protein I antibodies. Oral contraceptive use increases the risk of elevated antiphospholipid antibody levels among asymptomatic young women.

Original languageHungarian
Pages (from-to)3-7
Number of pages5
JournalMagyar Noorvosok Lapja
Volume66
Issue number1
Publication statusPublished - 2003

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Antiphospholipid Antibodies
Oral Contraceptives
Thrombophilia
Antibodies
Anticardiolipin Antibodies
Thromboembolism
Immunoglobulin A
Glycoproteins
Cross-Sectional Studies
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Serum
Proteins

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Foszfolipid-ellenes antitestek elo″fordulása fiatal no″kben kombinált orális fogamzásgátló szedése mellett. / Szilvia, Vad; Gabriella, Lakos; Kiss, E.; Erika, Peto; Róbert, Póka.

In: Magyar Noorvosok Lapja, Vol. 66, No. 1, 2003, p. 3-7.

Research output: Contribution to journalArticle

Szilvia, Vad ; Gabriella, Lakos ; Kiss, E. ; Erika, Peto ; Róbert, Póka. / Foszfolipid-ellenes antitestek elo″fordulása fiatal no″kben kombinált orális fogamzásgátló szedése mellett. In: Magyar Noorvosok Lapja. 2003 ; Vol. 66, No. 1. pp. 3-7.
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