The potential role of oxytocin and perinatal factors in the pathogenesis of autism spectrum disorders – review of the literature

Melinda Vanya, Szabina Szucs, Agnes Vetro, Gyorgy Bartfai

Research output: Contribution to journalArticle

8 Citations (Scopus)


Autism Spectrum Disorders (ASD) are characterized by: social and communication impairments, and by restricted repetitive behaviors. The aim of the present paper is to review abnormalities of oxytocin (OXT) and related congenital malformations in ASD. A literature search was conducted in the PubMed database up to 2016 for articles related to the pathomechanism of ASD, abnormalities of OXT and the OXT polymorphism in ASD. The pathomechanism of ASD has yet to be. The development of ASD is suggested to be related to abnormalities of the oxytocin-arginin-vasopressin system. Previous results suggest that OXT and arginine vasopressin (AVP) may play a role in the etiopathogenesis of ASD.

Original languageEnglish
Pages (from-to)288-290
Number of pages3
JournalPsychiatry research
Publication statusPublished - Jan 1 2017



  • Autism spectrum disorder, behavior
  • Cesarean section, oxytocin, oxytocin-receptor polymorphism
  • Gene

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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