A losartan pleiotrop hatásai: A húgysavszintcsö kkentés jelentocombining double acute accentsége

Translated title of the contribution: The pleiotrope effects of losartan - The importance of decreasing uric acid level

Csiky Botond, Markó Lajos, Mohás Márton, Cseh Judit, Mikolás Esztella, Szíjártó István, Wittmann István

Research output: Contribution to journalReview article

1 Citation (Scopus)


Nowdays the goal of the antihypertensive treatment is to decrease the cardiovascular risk of the patients by treating the associated diseases and possible hypertensive end-organ damages. Losartan is an antihypertensive drug with all these capabilities and placebo-like side-effect profile. Besides the most important effects of losartan, which are mediated by blocking the angiotensin II. type 1. receptors, it also has other, molecule specific beneficial effects. The most important, well documented pleiotropic effect of losartan is its uricosuric effect. The pleiotropic effects together with the blockade of the angiotensin II. receptors are considered more and more important in the hypertensive end-organ protection and in the treatment of associated diseases in hypertensive patients.

Original languageHungarian
Pages (from-to)663-666
Number of pages4
JournalLege Artis Medicinae
Issue number10
Publication statusPublished - Oct 1 2008


ASJC Scopus subject areas

  • Medicine(all)

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