Az inzulinszerü növekedési faktor-I helye az akromegalia aktivitásának megítélésében.

Translated title of the contribution: The place of insulin-like growth factor I in the diagnosis of acromegaly

O. Dohán, M. Góth, I. Szabolcs, L. Kovács, Z. Kovács, G. Szilágyi

Research output: Contribution to journalArticle

Abstract

Insulin-like growth factor-I (IGF-I) and basal growth hormone (GH) (average of GH values measured at -20 an 0 minutes) levels were measured in 32 (29 treated, 3 untreated) patients with acromegaly. In 15 patients IGF-I and basal GH values were normal. In 12 patients both GH and IGF-I were elevated. In 5 cases normal basal GH and elevated IGF-I levels were found. We assume that elevated serum level of IGF-I is a reliable sign of acromegalic activity. Compared to this, the basal GH level proved to be a much less reliable indicator to predict or exclude active acromegaly (sensitivity: 0.7, specificity: 1, positive predictive value: 1, negative predictive value: 0.75).

Original languageHungarian
Pages (from-to)2301-2303
Number of pages3
JournalOrvosi Hetilap
Volume134
Issue number42
Publication statusPublished - Oct 17 1993

Fingerprint

Acromegaly
Insulin-Like Growth Factor I
Growth Hormone
Reference Values
Sensitivity and Specificity
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Az inzulinszerü növekedési faktor-I helye az akromegalia aktivitásának megítélésében. / Dohán, O.; Góth, M.; Szabolcs, I.; Kovács, L.; Kovács, Z.; Szilágyi, G.

In: Orvosi Hetilap, Vol. 134, No. 42, 17.10.1993, p. 2301-2303.

Research output: Contribution to journalArticle

@article{65a93fc4734b4feca0ad74dd420df8dc,
title = "Az inzulinszer{\"u} n{\"o}veked{\'e}si faktor-I helye az akromegalia aktivit{\'a}s{\'a}nak meg{\'i}t{\'e}l{\'e}s{\'e}ben.",
abstract = "Insulin-like growth factor-I (IGF-I) and basal growth hormone (GH) (average of GH values measured at -20 an 0 minutes) levels were measured in 32 (29 treated, 3 untreated) patients with acromegaly. In 15 patients IGF-I and basal GH values were normal. In 12 patients both GH and IGF-I were elevated. In 5 cases normal basal GH and elevated IGF-I levels were found. We assume that elevated serum level of IGF-I is a reliable sign of acromegalic activity. Compared to this, the basal GH level proved to be a much less reliable indicator to predict or exclude active acromegaly (sensitivity: 0.7, specificity: 1, positive predictive value: 1, negative predictive value: 0.75).",
author = "O. Doh{\'a}n and M. G{\'o}th and I. Szabolcs and L. Kov{\'a}cs and Z. Kov{\'a}cs and G. Szil{\'a}gyi",
year = "1993",
month = "10",
day = "17",
language = "Hungarian",
volume = "134",
pages = "2301--2303",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "42",

}

TY - JOUR

T1 - Az inzulinszerü növekedési faktor-I helye az akromegalia aktivitásának megítélésében.

AU - Dohán, O.

AU - Góth, M.

AU - Szabolcs, I.

AU - Kovács, L.

AU - Kovács, Z.

AU - Szilágyi, G.

PY - 1993/10/17

Y1 - 1993/10/17

N2 - Insulin-like growth factor-I (IGF-I) and basal growth hormone (GH) (average of GH values measured at -20 an 0 minutes) levels were measured in 32 (29 treated, 3 untreated) patients with acromegaly. In 15 patients IGF-I and basal GH values were normal. In 12 patients both GH and IGF-I were elevated. In 5 cases normal basal GH and elevated IGF-I levels were found. We assume that elevated serum level of IGF-I is a reliable sign of acromegalic activity. Compared to this, the basal GH level proved to be a much less reliable indicator to predict or exclude active acromegaly (sensitivity: 0.7, specificity: 1, positive predictive value: 1, negative predictive value: 0.75).

AB - Insulin-like growth factor-I (IGF-I) and basal growth hormone (GH) (average of GH values measured at -20 an 0 minutes) levels were measured in 32 (29 treated, 3 untreated) patients with acromegaly. In 15 patients IGF-I and basal GH values were normal. In 12 patients both GH and IGF-I were elevated. In 5 cases normal basal GH and elevated IGF-I levels were found. We assume that elevated serum level of IGF-I is a reliable sign of acromegalic activity. Compared to this, the basal GH level proved to be a much less reliable indicator to predict or exclude active acromegaly (sensitivity: 0.7, specificity: 1, positive predictive value: 1, negative predictive value: 0.75).

UR - http://www.scopus.com/inward/record.url?scp=0027919501&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027919501&partnerID=8YFLogxK

M3 - Article

C2 - 8233444

AN - SCOPUS:0027919501

VL - 134

SP - 2301

EP - 2303

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 42

ER -