Az inzulinszerü növekedési faktor-I helye az akromegalia aktivitásának megítélésében.

Translated title of the contribution: The place of insulin-like growth factor I in the diagnosis of acromegaly

O. Dohán, M. Góth, I. Szabolcs, L. Kovács, Z. Kovács, G. Szilágyi

Research output: Contribution to journalArticle


Insulin-like growth factor-I (IGF-I) and basal growth hormone (GH) (average of GH values measured at -20 an 0 minutes) levels were measured in 32 (29 treated, 3 untreated) patients with acromegaly. In 15 patients IGF-I and basal GH values were normal. In 12 patients both GH and IGF-I were elevated. In 5 cases normal basal GH and elevated IGF-I levels were found. We assume that elevated serum level of IGF-I is a reliable sign of acromegalic activity. Compared to this, the basal GH level proved to be a much less reliable indicator to predict or exclude active acromegaly (sensitivity: 0.7, specificity: 1, positive predictive value: 1, negative predictive value: 0.75).

Original languageHungarian
Pages (from-to)2301-2303
Number of pages3
JournalOrvosi hetilap
Issue number42
Publication statusPublished - Oct 17 1993


ASJC Scopus subject areas

  • Medicine(all)

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