A total of 131 neonates was subdivided into 5 groups, in which the serum bilirubin level was determined every day during the first 8 days of life. The first group served as the control group, the other groups were subjected to the following methods of treatment: group II: continuous photic treatment; group III: daily administration of phenobarbital, 5 mg per kg intramuscularly in 2 divided doses; group IV: photic treatment from the first day, with added barbiturate treatment from the third day; group V: photic and barbiturate treatment from the first day. The bilirubin level was decreased by photics as well as by barbiturate treatment, but in those cases in which the hyperbilirubinemia remained within the limits of normal for neonates, the effect of the light was of less intensity, and not significant. The effect of the barbiturate treatment was significant from the 5th day on. The peak of the curve is lowered, and displaced from the 5th to the 3rd day. This treatment reduced the number of exchange transfusions required by almost 80%.
|Translated title of the contribution||The photic and barbiturate treatment of icterus neonatorum|
|Number of pages||7|
|Journal||Acta paediatrica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1973|
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