The Phagocytic Function of the Reticuloendothelial System in Rats Treated with Polybrene®, Liquoid® and Compound 48/80

G. Lazar, F. Biliczki, K. Kovács

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The phagocytic function of the reticuloendothelial system was studied in rats by India ink clearance and histological examination. Twelve hours fol lowing Ihe intravenous administration of Polybrene or Liquoid the phagocytic activity of Ihe reticuloendothelial system in rats decreased, whereas after treatment with Compound 48/80 it remained unchanged. One hour after injection of Polybrene or Liquoid a significant amount of the intravenously administered India ink was lodged in Ihe lungs. Owing lo Ihe Inlrapulmonary India ink accumulation the phagocytic function of the HKS could not be evaluated at this period.

Original languageEnglish
Pages (from-to)253-262
Number of pages10
JournalPharmacology
Volume1
Issue number4
DOIs
Publication statusPublished - 1968

Fingerprint

Polyanetholesulfonate
Hexadimethrine Bromide
p-Methoxy-N-methylphenethylamine
Mononuclear Phagocyte System
Intravenous Administration
Lung
Injections
chinese ink
Therapeutics

Keywords

  • Compound 48/80
  • Liquoid®
  • Polybrene®
  • RES Phagocytic function

ASJC Scopus subject areas

  • Pharmacology

Cite this

The Phagocytic Function of the Reticuloendothelial System in Rats Treated with Polybrene®, Liquoid® and Compound 48/80. / Lazar, G.; Biliczki, F.; Kovács, K.

In: Pharmacology, Vol. 1, No. 4, 1968, p. 253-262.

Research output: Contribution to journalArticle

@article{e177046959624dbc8c86cb8196cf8bf1,
title = "The Phagocytic Function of the Reticuloendothelial System in Rats Treated with Polybrene{\circledR}, Liquoid{\circledR} and Compound 48/80",
abstract = "The phagocytic function of the reticuloendothelial system was studied in rats by India ink clearance and histological examination. Twelve hours fol lowing Ihe intravenous administration of Polybrene or Liquoid the phagocytic activity of Ihe reticuloendothelial system in rats decreased, whereas after treatment with Compound 48/80 it remained unchanged. One hour after injection of Polybrene or Liquoid a significant amount of the intravenously administered India ink was lodged in Ihe lungs. Owing lo Ihe Inlrapulmonary India ink accumulation the phagocytic function of the HKS could not be evaluated at this period.",
keywords = "Compound 48/80, Liquoid{\circledR}, Polybrene{\circledR}, RES Phagocytic function",
author = "G. Lazar and F. Biliczki and K. Kov{\'a}cs",
year = "1968",
doi = "10.1159/000135972",
language = "English",
volume = "1",
pages = "253--262",
journal = "Pharmacology",
issn = "0031-7012",
publisher = "S. Karger AG",
number = "4",

}

TY - JOUR

T1 - The Phagocytic Function of the Reticuloendothelial System in Rats Treated with Polybrene®, Liquoid® and Compound 48/80

AU - Lazar, G.

AU - Biliczki, F.

AU - Kovács, K.

PY - 1968

Y1 - 1968

N2 - The phagocytic function of the reticuloendothelial system was studied in rats by India ink clearance and histological examination. Twelve hours fol lowing Ihe intravenous administration of Polybrene or Liquoid the phagocytic activity of Ihe reticuloendothelial system in rats decreased, whereas after treatment with Compound 48/80 it remained unchanged. One hour after injection of Polybrene or Liquoid a significant amount of the intravenously administered India ink was lodged in Ihe lungs. Owing lo Ihe Inlrapulmonary India ink accumulation the phagocytic function of the HKS could not be evaluated at this period.

AB - The phagocytic function of the reticuloendothelial system was studied in rats by India ink clearance and histological examination. Twelve hours fol lowing Ihe intravenous administration of Polybrene or Liquoid the phagocytic activity of Ihe reticuloendothelial system in rats decreased, whereas after treatment with Compound 48/80 it remained unchanged. One hour after injection of Polybrene or Liquoid a significant amount of the intravenously administered India ink was lodged in Ihe lungs. Owing lo Ihe Inlrapulmonary India ink accumulation the phagocytic function of the HKS could not be evaluated at this period.

KW - Compound 48/80

KW - Liquoid®

KW - Polybrene®

KW - RES Phagocytic function

UR - http://www.scopus.com/inward/record.url?scp=0014371021&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014371021&partnerID=8YFLogxK

U2 - 10.1159/000135972

DO - 10.1159/000135972

M3 - Article

C2 - 4178660

AN - SCOPUS:0014371021

VL - 1

SP - 253

EP - 262

JO - Pharmacology

JF - Pharmacology

SN - 0031-7012

IS - 4

ER -