The PEACE project: General discussion

W. Roemer, G. Hoek, B. Brunekreef, J. P. Schouten, G. Baldini, J. Clench-Aas, N. Englert, P. Fischer, B. Forsberg, J. Haluszka, A. Kalandidi, F. Kotesovec, G. Niepsuj, J. Pekkanen, P. Rudnai, S. Skerfving, V. Vondra, H. E. Wichmann, D. Dockery, J. Schwartz

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The Pollution Effects on Asthmatic Children in Europe (PEACE) study has developed and tested methods for panel studies as a methodology for assessing the relationship between short-term changes in air pollution and short-term changes in health status of children with chronic respiratory symptoms. The PEACE study has shown that in the winter of 1993-1994, large gradients in particles with a 50% cut-off aerodynamic diameter of 10 μm (PM10) levels across Europe existed from north to south. The difference in PM10 level between urban and control locations was in most study areas quite small. Overall, no clear association between changes in peak expiratory flow and changes in air pollution or between changes in incidence or prevalence of respiratory symptoms and changes in air pollution could be detected. Possible explanations of this lack of effect are discussed. In some of the locations, air pollution levels may have been too low to result in demonstrable, acute effects on respiratory health. Children with nightly coughing as their only screening symptom may not react to air pollution, reducing the association for the whole panel to insignificance. Respiratory infections could have obscured or even reversed the association between air pollution and respiratory health indicators. Nondifferential exposure misclassification may have biased the association towards the null. In conclusion, in most panels no clear relation could be established between day-to-day changes in air pollution and changes in respiratory health.

Original languageEnglish
Pages (from-to)125-130
Number of pages6
JournalEuropean Respiratory Review
Volume8
Issue number52
Publication statusPublished - Jan 1 1998

Keywords

  • Air pollution
  • Children
  • PM10
  • Panel study
  • Peak expiratory flow
  • Respiratory symptoms

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Roemer, W., Hoek, G., Brunekreef, B., Schouten, J. P., Baldini, G., Clench-Aas, J., Englert, N., Fischer, P., Forsberg, B., Haluszka, J., Kalandidi, A., Kotesovec, F., Niepsuj, G., Pekkanen, J., Rudnai, P., Skerfving, S., Vondra, V., Wichmann, H. E., Dockery, D., & Schwartz, J. (1998). The PEACE project: General discussion. European Respiratory Review, 8(52), 125-130.