A nagy thrombocytaszámmal járó kórképek elkülönítése az O'Brien-féle filter-teszt segítségével.

Translated title of the contribution: The O'Brien filter test in the differential diagnosis of disorders with high-grade thrombocytosis

L. Rejtö, A. Schlammadinger, P. László, A. Kiss, B. Telek, Z. Boda

Research output: Contribution to journalArticle

Abstract

In the differential diagnosis of primary and secondary thrombocytosis, platelet function test can be used. We have examined the possible role of O'Brien's filter test in the differentiation of primary and secondary thrombocytosis in 53 patients with myeloproliferative diseases with primary thrombocytosis and in 21 patients with other disorders complicated by secondary thrombocytosis. By using heparin as an anticoagulant, the sensitivity of O'Brien's filter test proved to be 75%, and it's specificity was 85.7%. In blood samples anticoagulated with citrate, the sensitivity was 100% and specificity 83.3%. Based on these studies we suggest the use of O'Brien's filterometer as a screening test in the differential diagnosis in patients with elevated (> 400 x 10(9)/L) platelet count. In case of normal results, the causes of reactive thrombocytosis should be cleared first, while with pathologic results, haematological examination of the patients should be performed.

Original languageHungarian
Pages (from-to)1961-1964
Number of pages4
JournalOrvosi hetilap
Volume139
Issue number33
Publication statusPublished - Aug 16 1998

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rejtö, L., Schlammadinger, A., László, P., Kiss, A., Telek, B., & Boda, Z. (1998). A nagy thrombocytaszámmal járó kórképek elkülönítése az O'Brien-féle filter-teszt segítségével. Orvosi hetilap, 139(33), 1961-1964.