Chiptechnikák alkalmazása vastagbélrákban

Translated title of the contribution: The need of chip-techniques in colorectal cancer

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The examination of gene expression in colorectal cancer may develope the bases of early diagnosis and of individual therapeutic strategies. With the few cDNA microarray examinations in colorectal cancer the expression of hundreds and thousands of genes were studied, although both the sample collection and the final results showed differencies. Beside the exposition of the practical advantages of the chip technology our aims are the standardization of the currently available data in the international scientific literature and the description of the results in a comprehensible way. To summarize one can say that gene expression examinations in colorectal cancer show the accentuated role in carcinogenesis of not only the tumor suppressor, apoptosis- or cell-cycle regulation related genes, but of some mitochondrial, metabolic and cell-cell or cell-extracellular matrix conjunction gene families.

Original languageHungarian
Pages (from-to)993-999
Number of pages7
JournalOrvosi Hetilap
Volume145
Issue number19
Publication statusPublished - May 2004

Fingerprint

Colorectal Neoplasms
Literature
Gene Expression
Mitochondrial Genes
Oligonucleotide Array Sequence Analysis
Genes
Extracellular Matrix
Early Diagnosis
Cell Cycle
Carcinogenesis
Apoptosis
Technology
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chiptechnikák alkalmazása vastagbélrákban. / Sípos, F.; Galamb, O.; Molnár, B.; Tulassay, Z.

In: Orvosi Hetilap, Vol. 145, No. 19, 05.2004, p. 993-999.

Research output: Contribution to journalArticle

@article{16c6702279c84fffacc8432ce3f9fbd2,
title = "Chiptechnik{\'a}k alkalmaz{\'a}sa vastagb{\'e}lr{\'a}kban",
abstract = "The examination of gene expression in colorectal cancer may develope the bases of early diagnosis and of individual therapeutic strategies. With the few cDNA microarray examinations in colorectal cancer the expression of hundreds and thousands of genes were studied, although both the sample collection and the final results showed differencies. Beside the exposition of the practical advantages of the chip technology our aims are the standardization of the currently available data in the international scientific literature and the description of the results in a comprehensible way. To summarize one can say that gene expression examinations in colorectal cancer show the accentuated role in carcinogenesis of not only the tumor suppressor, apoptosis- or cell-cycle regulation related genes, but of some mitochondrial, metabolic and cell-cell or cell-extracellular matrix conjunction gene families.",
keywords = "Colorectal cancer, Gene expression, Microarray technology",
author = "F. S{\'i}pos and O. Galamb and B. Moln{\'a}r and Z. Tulassay",
year = "2004",
month = "5",
language = "Hungarian",
volume = "145",
pages = "993--999",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "19",

}

TY - JOUR

T1 - Chiptechnikák alkalmazása vastagbélrákban

AU - Sípos, F.

AU - Galamb, O.

AU - Molnár, B.

AU - Tulassay, Z.

PY - 2004/5

Y1 - 2004/5

N2 - The examination of gene expression in colorectal cancer may develope the bases of early diagnosis and of individual therapeutic strategies. With the few cDNA microarray examinations in colorectal cancer the expression of hundreds and thousands of genes were studied, although both the sample collection and the final results showed differencies. Beside the exposition of the practical advantages of the chip technology our aims are the standardization of the currently available data in the international scientific literature and the description of the results in a comprehensible way. To summarize one can say that gene expression examinations in colorectal cancer show the accentuated role in carcinogenesis of not only the tumor suppressor, apoptosis- or cell-cycle regulation related genes, but of some mitochondrial, metabolic and cell-cell or cell-extracellular matrix conjunction gene families.

AB - The examination of gene expression in colorectal cancer may develope the bases of early diagnosis and of individual therapeutic strategies. With the few cDNA microarray examinations in colorectal cancer the expression of hundreds and thousands of genes were studied, although both the sample collection and the final results showed differencies. Beside the exposition of the practical advantages of the chip technology our aims are the standardization of the currently available data in the international scientific literature and the description of the results in a comprehensible way. To summarize one can say that gene expression examinations in colorectal cancer show the accentuated role in carcinogenesis of not only the tumor suppressor, apoptosis- or cell-cycle regulation related genes, but of some mitochondrial, metabolic and cell-cell or cell-extracellular matrix conjunction gene families.

KW - Colorectal cancer

KW - Gene expression

KW - Microarray technology

UR - http://www.scopus.com/inward/record.url?scp=3142782397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3142782397&partnerID=8YFLogxK

M3 - Article

C2 - 15181734

AN - SCOPUS:3142782397

VL - 145

SP - 993

EP - 999

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 19

ER -