THE MECHANISM OF THE MOTOR RESPONSE TO PERIARTERIAL NERVE STIMULATION IN THE SMALL INTESTINE OF THE RABBIT

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26 Citations (Scopus)

Abstract

In the presence of guanethidine, periarterial nerve stimulation caused a frequency‐dependent motor response in the rabbit isolated ileum. Tachyphylaxis to capsaicin greatly diminished the effect of periarterial stimulation; the remaining portion of the contractile response was susceptible to hexamethonium. The motor effect of periarterial stimulation is mediated by two different mechanisms: one via parasympathetic preganglionic nerves and the other sensitive to capsaicin. 1980 British Pharmacological Society

Original languageEnglish
Pages (from-to)193-195
Number of pages3
JournalBritish journal of pharmacology
Volume70
Issue number2
DOIs
Publication statusPublished - Oct 1980

ASJC Scopus subject areas

  • Pharmacology

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