The lymphocytes in elderly individuals and centenarians

E. Beregi, O. Regius, K. Rajczy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The structure of lymphocytes and immune parameters were examined in 123 elderly (60-69 years of age) and 118 centenarian subjects. Age related degenerative changes in the mitochondria of lymphocytes proved to be more frequent in the centenarians, but the occurrence of giant mitochondria were not significantly increased. Lipofuscin and tubuloreticular inclusions were significantly more frequent in the cytoplasm of the lymphocytes of centenarians than in that of the younger age group. The absolute T cell number, serum IgG levels and morphological changes in the lymphocytes correlated with the absolute number of lymphocytes, B cell number and antinuclear factor.

Original languageEnglish
Pages (from-to)515-518
Number of pages4
JournalArchives of Gerontology and Geriatrics
Volume12
Issue numberSUPPL. 2
Publication statusPublished - 1991

Fingerprint

Lymphocytes
age group
Mitochondria
Cell Count
inclusion
Lipofuscin
Antinuclear Antibodies
Lymphocyte Count
Cytoplasm
B-Lymphocytes
Age Groups
Immunoglobulin G
T-Lymphocytes
Serum

Keywords

  • aging of lymphocytes
  • centenarians
  • immune senescence
  • mitochondria in old lymphocytes

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)

Cite this

The lymphocytes in elderly individuals and centenarians. / Beregi, E.; Regius, O.; Rajczy, K.

In: Archives of Gerontology and Geriatrics, Vol. 12, No. SUPPL. 2, 1991, p. 515-518.

Research output: Contribution to journalArticle

Beregi, E. ; Regius, O. ; Rajczy, K. / The lymphocytes in elderly individuals and centenarians. In: Archives of Gerontology and Geriatrics. 1991 ; Vol. 12, No. SUPPL. 2. pp. 515-518.
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