The long-term cultivation and cryopreservation of human fetal pancreatic tissue

G. Farkas, G. Lazar, J. Herczegh

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Fetal human pancreatic islets were cultured and cryopreserved for long periods (18 weeks and 6-8 months, respectively). Multiplication of the cells was observed, and later differentiation as well. The growth characteristics and insulin-like immunoreactivity were evidenced by light microscopy, immunocytochemistry, electron microscopic examinations and measurement of the total insulin content. These results indicate that the cultivation and storage of fetal islets by cryopreservation are hopeful prodedures for future human islet transplantation.

Original languageEnglish
Pages (from-to)64-68
Number of pages5
JournalHormone and Metabolic Research
Volume25
Issue numberSUPPL.
Publication statusPublished - Dec 1 1990

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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