Comparative fine structural investigations made on frog, chicken, rat, monkey and human retinas confirmed the presence of an amorphous intercellular substance, interphotoreceptor matrix, around the outer and inner segments of the visual cells. A higher concentration of the interphotoreceptor matrix was frequently found on the surface of the outer segments. Tubules in the apical cytoplasm of the pigment epithelial cells were often filled with substance of morphological similar appearance which may indicate the site of formation of the matrix. The acid mucopolysaccharide character of the matrix was demonstrated by light-microscopic histochemical (metachromasia, Alcian blue and Hale reaction) and electron histochemical observations (binding of colloidal iron, PTA staining at acid pH).
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience