The influence of colostral antibodies on the immunization of lambs against adenoviruses

V. Pálfi, S. Belák, S. Tuboly

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Abstract

The effect of colostral antibodies on the immune response in lambs following adenovirus vaccination was studied. Young lambs of different ages, born from vaccinated ewes, were vaccinated with an inactivated and aluminium hydroxide-adsorbed sheep adenovirus vaccine. In a group of lambs vaccinated at 5-7 days of age, the titre of humoral antibodies declined in parallel to unvaccinated controls. In lambs vaccinated at 24-35 days of age, antibody titres to adenovirus stabilised and persisted after an initial fall. Cell mediated immunity, as measured by blastogenic responses of circulating lymphocytes, was stimulated in both groups, but higher numbers of IgG-producing cells became evident in the group of lambs vaccinated at 24-35 days of age.

Original languageEnglish
Pages (from-to)191-196
Number of pages6
JournalVeterinary Microbiology
Volume6
Issue number3
DOIs
Publication statusPublished - Sep 1981

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ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

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