The importance of postoperative CT image fusion verification of stereotactic interstitial irradiation for brain tumors

Arpad Viola, Tibor Major, Jeno Julow

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Purpose The aim of our study was verification of the position of implanted catheters with 125I seeds after the catheter implantation for the brachytherapy of brain tumors. Methods and materials The fusion of the CT image used at planning and after the implantation of the catheters enabled us to verify the position of the catheters containing the isotopes. After this, the tumor volume covered by the prescribed dose (TVPD) and the normal tissue volume covered by the prescribed dose (NTVPD) were compared between the plan and the actual result. The image fusion was performed by the BrainLab-Target 1.19 software on an Alfa 430 (Digital) workstation. Results The position of the catheters was adjusted in 14 (20%) of the 70 image fusion cases being studied. The position of 16 of the 116 catheters (13.8%) required adjustment after the fusion of control images in the 70 cases studied. The Student t probe revealed a significant difference between the TVPD values of the reality and the plans (75.8% vs. 92.4%, p < 0.0001). There was a significant difference between values of the real performances and planning for NTVPD (86.8% vs. 76%, p = 0.001) and for the conformity index (0.37 vs. 0.54, p = 0.0001), too. Conclusion The application of the interstitial irradiation with CT control allows us to identify and correct possible inaccuracies in catheter positioning during the operation. The procedure then becomes far more accurate and reliable, and as such, the irradiation becomes more conformal than without catheter adjustment.

Original languageEnglish
Pages (from-to)322-328
Number of pages7
JournalInternational Journal of Radiation Oncology Biology Physics
Volume60
Issue number1
DOIs
Publication statusPublished - Sep 1 2004

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Keywords

  • Brain tumors
  • I brachytherapy
  • Image fusion
  • Verification

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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