A mikronizálás jelentosége a gyó gyszerformák tervezésében II. Gyó gyszertechnológiai vonatkozások

Translated title of the contribution: The importance of micronization in the design of dosage forms II. Pharmaceutical technological considerations

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The role of particle size reduction and particle engineering is growing considering the design and manufacturing of drug carrier systems. The objective of the review is to summarize and compare the micronization methods based on particle size reduction and which are applied to improve drug dissolution and bioavailability. These methods are effective especially when suitable pharmaceutical excipients are used by co-grinding. Beside formation of engineered particles, milling remains important to design particles with the desired size, shape and surface characteristics.

Original languageHungarian
Pages (from-to)149-154
Number of pages6
JournalActa Pharmaceutica Hungarica
Volume76
Issue number3
Publication statusPublished - 2006

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Dosage Forms
Particle Size
Drug Carriers
Excipients
Pharmaceutical Preparations
Biological Availability
Drug Liberation

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

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title = "A mikroniz{\'a}l{\'a}s jelentos{\'e}ge a gy{\'o} gyszerform{\'a}k tervez{\'e}s{\'e}ben II. Gy{\'o} gyszertechnol{\'o}giai vonatkoz{\'a}sok",
abstract = "The role of particle size reduction and particle engineering is growing considering the design and manufacturing of drug carrier systems. The objective of the review is to summarize and compare the micronization methods based on particle size reduction and which are applied to improve drug dissolution and bioavailability. These methods are effective especially when suitable pharmaceutical excipients are used by co-grinding. Beside formation of engineered particles, milling remains important to design particles with the desired size, shape and surface characteristics.",
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