A lézer-mikrodisszekció jelentosége és gyakorlati alkalmazása a klinikai kutatásban és a diagnosztikai módszerfejlesztésben.

Translated title of the contribution: The importance and use of laser microdissection in clinical research and diagnostic method development

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1 Citation (Scopus)

Abstract

The molecular biological analysis of rare cell samples has become increasingly important in medical research and applications. Using laser microdissection and special macromolecule isolation techniques allows us to understand the biological information even in a single cell and to examine the genetical and proteomical features of biologically homogenous cell populations. There are several type of laser microdissectors which have a very user-friendly actuation. In practice the most difficult parts are the sample preparation and the macromolecule extraction from rare cell samples. The aims of this study are to summarize current practical experiences and to foreshow the application possibilities of this quite new technique in clinical practice.

Original languageHungarian
Pages (from-to)1355-1361
Number of pages7
JournalOrvosi Hetilap
Volume145
Issue number26
Publication statusPublished - Jun 27 2004

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Microdissection
Lasers
Research
Biomedical Research
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "A l{\'e}zer-mikrodisszekci{\'o} jelentos{\'e}ge {\'e}s gyakorlati alkalmaz{\'a}sa a klinikai kutat{\'a}sban {\'e}s a diagnosztikai m{\'o}dszerfejleszt{\'e}sben.",
abstract = "The molecular biological analysis of rare cell samples has become increasingly important in medical research and applications. Using laser microdissection and special macromolecule isolation techniques allows us to understand the biological information even in a single cell and to examine the genetical and proteomical features of biologically homogenous cell populations. There are several type of laser microdissectors which have a very user-friendly actuation. In practice the most difficult parts are the sample preparation and the macromolecule extraction from rare cell samples. The aims of this study are to summarize current practical experiences and to foreshow the application possibilities of this quite new technique in clinical practice.",
author = "F. S{\'i}pos and Dominika Szoke and O. Galamb and B. Moln{\'a}r and Z. Tulassay",
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AU - Szoke, Dominika

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AU - Molnár, B.

AU - Tulassay, Z.

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