The importance and clinical characteristics of gastro-oesophageal reflux in infants and young children. Differences of manifestations as compared to adulthood

Research output: Contribution to journalArticle


In the last 20 years there has been an explosive growth of knowledge about gastrointestinal motility, its disorders manifesting as hypo- or hypermotility in clinical cases. The main representative of hypermotility syndromes is the gastro-oesophageal reflux disease (GORD) (1). GOR gained increasing attention in international paediatric literature in the second half of the 1970s. Its importance is highlighted by the fact, that the European Society for Paediatric Gastroenterology and Nutrition (ESPGAN) created a Working Group for it, and issued guidelines for diagnosis and treatment (25, 26, 30). Our interest was drawn to the topic in 1984, when we started intraoesophageal pH recordings and we communicated our experiences at congresses and in literature (1, 27, 28). By doing continuous oesophageal pH measurements it became clear, that GOR should be anticipated more often during infancy when the disease is usually mild and self-limiting, but it can cause severe illness and might lead to death. The biggest problems that it is a many facted syndrome, in several illnesses GO can be an underlying cause as a pathogenic factor, and it is a clinical entity which crosses interdisciplinary boundaries. It is hard to find a subspeciality within paediatrics, in which GOR does not appear as a possible diagnosis. On the other hand, the reflux syndrome can involve a wide differential diagnostic spectrum.

Original languageEnglish
Pages (from-to)99-101
Number of pages3
JournalPaediatria Croatica
Issue number2
Publication statusPublished - Jan 1 1995


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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