The Hungarian validation of the brief international cognitive assessment for multiple sclerosis (BICAMS) battery and the correlation of cognitive impairment with fatigue and quality of life

Dániel Sandi, Tibor Rudisch, Judit Füvesi, Zsanett Fricska-Nagy, Hajnalka Huszka, Tamás Biernacki, Dawn W. Langdon, Éva Langane, L. Vécsei, K. Bencsik

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Background Multiple Sclerosis (MS) causes not only somatic, but also cognitive impairment regardless of the patients' age or the course of the disease. The Brief International Cognitive Assessment for MS (BICAMS) test, published in 2011, is a short cognitive questionnaire: a fast, reliable, sensitive and specific tool for the evaluation of the patients' cognitive state. Objectives Our primary objective was to assess the validity of the Hungarian version of the BICAMS test. Our secondary objective was to evaluate the impact of the cognitive impairment on the patient's quality of life and fatigue's impact on the patients' cognitive state. Methods 65 RR-MS patients and 65 age, sex and education matched healthy control (HC) subjects completed the test and were retested after 3 weeks. The patients also completed the MS Quality of Life 54 (MSQoL54) and the Fatigue Impact Scale (FIS) assessments. Group differences were calculated by paired sample T-tests. The test-retest reliability was measured by intraclass correlation coefficients. To analyze the difference between the test-retest performances of the two groups we used two-way repeated measures ANOVA where the BICAMS battery was the single composite outcome and one-way repeated measures ANOVA. To assess the impact of the cognitive decline on the patients' quality of life and fatigue's impact on the cognitive state, we examined the correlations between results in the BICAMS and the MSQoL54 and FIS. Results We found significant difference (p≤0.001, p=0.017 in the first CVLT-II assessment) between MS patients and members of the HC group in all four evaluated parameters of BICAMS test in both sessions. The correlation coefficients were very strong between the tests and retests (r;gt p;lt r=0.678, p

Original languageEnglish
Pages (from-to)499-504
Number of pages6
JournalMultiple Sclerosis and Related Disorders
Volume4
Issue number6
DOIs
Publication statusPublished - Nov 1 2015

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Multiple Sclerosis
Fatigue
Quality of Life
Analysis of Variance
Cognitive Dysfunction
Sex Education
Reproducibility of Results
Healthy Volunteers
Control Groups

Keywords

  • BICAMS
  • Cognition
  • Fatigue
  • Health-related quality of life
  • Multiple Sclerosis
  • Validation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

The Hungarian validation of the brief international cognitive assessment for multiple sclerosis (BICAMS) battery and the correlation of cognitive impairment with fatigue and quality of life. / Sandi, Dániel; Rudisch, Tibor; Füvesi, Judit; Fricska-Nagy, Zsanett; Huszka, Hajnalka; Biernacki, Tamás; Langdon, Dawn W.; Langane, Éva; Vécsei, L.; Bencsik, K.

In: Multiple Sclerosis and Related Disorders, Vol. 4, No. 6, 01.11.2015, p. 499-504.

Research output: Contribution to journalArticle

Sandi, Dániel ; Rudisch, Tibor ; Füvesi, Judit ; Fricska-Nagy, Zsanett ; Huszka, Hajnalka ; Biernacki, Tamás ; Langdon, Dawn W. ; Langane, Éva ; Vécsei, L. ; Bencsik, K. / The Hungarian validation of the brief international cognitive assessment for multiple sclerosis (BICAMS) battery and the correlation of cognitive impairment with fatigue and quality of life. In: Multiple Sclerosis and Related Disorders. 2015 ; Vol. 4, No. 6. pp. 499-504.
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abstract = "Background Multiple Sclerosis (MS) causes not only somatic, but also cognitive impairment regardless of the patients' age or the course of the disease. The Brief International Cognitive Assessment for MS (BICAMS) test, published in 2011, is a short cognitive questionnaire: a fast, reliable, sensitive and specific tool for the evaluation of the patients' cognitive state. Objectives Our primary objective was to assess the validity of the Hungarian version of the BICAMS test. Our secondary objective was to evaluate the impact of the cognitive impairment on the patient's quality of life and fatigue's impact on the patients' cognitive state. Methods 65 RR-MS patients and 65 age, sex and education matched healthy control (HC) subjects completed the test and were retested after 3 weeks. The patients also completed the MS Quality of Life 54 (MSQoL54) and the Fatigue Impact Scale (FIS) assessments. Group differences were calculated by paired sample T-tests. The test-retest reliability was measured by intraclass correlation coefficients. To analyze the difference between the test-retest performances of the two groups we used two-way repeated measures ANOVA where the BICAMS battery was the single composite outcome and one-way repeated measures ANOVA. To assess the impact of the cognitive decline on the patients' quality of life and fatigue's impact on the cognitive state, we examined the correlations between results in the BICAMS and the MSQoL54 and FIS. Results We found significant difference (p≤0.001, p=0.017 in the first CVLT-II assessment) between MS patients and members of the HC group in all four evaluated parameters of BICAMS test in both sessions. The correlation coefficients were very strong between the tests and retests (r;gt p;lt r=0.678, p",
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AU - Huszka, Hajnalka

AU - Biernacki, Tamás

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AB - Background Multiple Sclerosis (MS) causes not only somatic, but also cognitive impairment regardless of the patients' age or the course of the disease. The Brief International Cognitive Assessment for MS (BICAMS) test, published in 2011, is a short cognitive questionnaire: a fast, reliable, sensitive and specific tool for the evaluation of the patients' cognitive state. Objectives Our primary objective was to assess the validity of the Hungarian version of the BICAMS test. Our secondary objective was to evaluate the impact of the cognitive impairment on the patient's quality of life and fatigue's impact on the patients' cognitive state. Methods 65 RR-MS patients and 65 age, sex and education matched healthy control (HC) subjects completed the test and were retested after 3 weeks. The patients also completed the MS Quality of Life 54 (MSQoL54) and the Fatigue Impact Scale (FIS) assessments. Group differences were calculated by paired sample T-tests. The test-retest reliability was measured by intraclass correlation coefficients. To analyze the difference between the test-retest performances of the two groups we used two-way repeated measures ANOVA where the BICAMS battery was the single composite outcome and one-way repeated measures ANOVA. To assess the impact of the cognitive decline on the patients' quality of life and fatigue's impact on the cognitive state, we examined the correlations between results in the BICAMS and the MSQoL54 and FIS. Results We found significant difference (p≤0.001, p=0.017 in the first CVLT-II assessment) between MS patients and members of the HC group in all four evaluated parameters of BICAMS test in both sessions. The correlation coefficients were very strong between the tests and retests (r;gt p;lt r=0.678, p

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