The Hungarian congenital malformation monitoring system

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The Hungarian Congenital Malformation Monitor has been operating since 1973 in order to detect the temporal and regional clusters of 12 indicator congenital malformations as early as possible. This Monitor takes part in the International Clearinghouse for Birth Defects Monitoring System. Three continuously increasing trends were detected in 1973-1976. They may be connected with the more complete notifications, although the increase of limb reduction deformities is only partly explained by this factor. Transitional (quarterly) significant clusters were observed in the case of anencephaly (1974, IV), spina bifida (1974, II; 1975, III; 1976, III), cleft lip with or without cleft palate (1974, III). The possibility of three technical biases (changes in diagnosis, notification and evaluation of the given congenital malformation) has to be excluded before accepting the fact of a real epidemic. Subsequently a case-control epidemiological study by personal interviews and with matched controls has to be performed.

Original languageEnglish
Pages (from-to)225-238
Number of pages14
JournalActa Paediatrica Academiae Scientiarum Hungaricae
Volume19
Issue number3
Publication statusPublished - 1978

Fingerprint

Anencephaly
Spinal Dysraphism
Cleft Lip
Cleft Palate
Case-Control Studies
Epidemiologic Studies
Extremities
Interviews

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The Hungarian congenital malformation monitoring system. / Czeizel, E.

In: Acta Paediatrica Academiae Scientiarum Hungaricae, Vol. 19, No. 3, 1978, p. 225-238.

Research output: Contribution to journalArticle

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