The hormonal system of the unicellular Tetrahymena

A review with evolutionary aspects

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The unicellular ciliate, Tetrahymena has receptors for hormones of the higher ranked animals, these hormones (e.g. insulin, triiodothyronine, ACTH, histamine, etc.) are also produced by it and it has signal pathways and second messengers for signal transmission. These components are chemically and functionally very similar to that of mammalian ones. The exogenously given hormones regulate different functions, as movement, phagocytosis, chemotaxis, cell growth, secretion, excretion and the cells' own hormone production. The receptors are extremely sensitive, certain hormones are sensed (and response is provoked) at 10-21 M concentration, which makes likely that the function could work by the effect of hormones produced by the Tetrahymena itself. The signal reception is selective, it can differentiate between closely related hormones. The review is listing the hormones produced by the Tetrahymena, the receptors which can receive signals and the signal pathways and second messengers as well, as the known effects of mammalian hormones to the life functions of Tetrahymena. The possible and justified role of hormonal system in the Tetrahymena as a single cell and inside the Tetrahymena population, as a community is discussed. The unicellular hormonal system and mammalian endocrine system are compared and evolutionary conclusions are drawn.

Original languageEnglish
Pages (from-to)131-156
Number of pages26
JournalActa Microbiologica et Immunologica Hungarica
Volume59
Issue number2
DOIs
Publication statusPublished - Jun 1 2012

Fingerprint

Tetrahymena
Hormones
Second Messenger Systems
Signal Transduction
Cytophagocytosis
Endocrine System
Triiodothyronine
Chemotaxis
Adrenocorticotropic Hormone
Histamine
Insulin

Keywords

  • evolution
  • hormone receptors
  • hormones
  • Protozoan
  • signal transduction
  • Tetrahymena

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Medicine(all)

Cite this

The hormonal system of the unicellular Tetrahymena : A review with evolutionary aspects. / Csaba, G.

In: Acta Microbiologica et Immunologica Hungarica, Vol. 59, No. 2, 01.06.2012, p. 131-156.

Research output: Contribution to journalArticle

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