Az elhízás genetikája

Translated title of the contribution: The genetics of obesity

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Obesity is a major health problem. It increases the risk of cardiovascular diseases, 2-type diabetes mellitus, cancers, and premature mortality. Apart from some monogenic forms, it's a polygenic disorder, the result of interaction of genes and environmental factors. Genetic variants of proteins taking part in the regulation of food intake or thermogenesis and tissue mediators produced by the adipose tissue are responsible the genetic components of obesity. Identification of the genetic background of the obesity will help to understand the exact molecular mechanism of the pathogenesis, make possible the prevention, as well as individual therapeutic interventions.

Original languageHungarian
Pages (from-to)107-113
Number of pages7
JournalOrvosi Hetilap
Volume147
Issue number3
Publication statusPublished - Jan 22 2006

Fingerprint

Obesity
Appetite Regulation
Premature Mortality
Thermogenesis
Type 2 Diabetes Mellitus
Adipose Tissue
Cardiovascular Diseases
Health
Genes
Neoplasms
Proteins
Therapeutics
Genetic Background

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Az elhízás genetikája. / Hagymási, K.; Tulassay, Z.

In: Orvosi Hetilap, Vol. 147, No. 3, 22.01.2006, p. 107-113.

Research output: Contribution to journalArticle

Hagymási, K. ; Tulassay, Z. / Az elhízás genetikája. In: Orvosi Hetilap. 2006 ; Vol. 147, No. 3. pp. 107-113.
@article{fc47d6cc8cdb48dc8c3a995170559c27,
title = "Az elh{\'i}z{\'a}s genetik{\'a}ja",
abstract = "Obesity is a major health problem. It increases the risk of cardiovascular diseases, 2-type diabetes mellitus, cancers, and premature mortality. Apart from some monogenic forms, it's a polygenic disorder, the result of interaction of genes and environmental factors. Genetic variants of proteins taking part in the regulation of food intake or thermogenesis and tissue mediators produced by the adipose tissue are responsible the genetic components of obesity. Identification of the genetic background of the obesity will help to understand the exact molecular mechanism of the pathogenesis, make possible the prevention, as well as individual therapeutic interventions.",
keywords = "β3 adrenergic receptor, Genetics, Leptin, Obesity, Peroxisome-proliferator activated receptor-γ, Polygenic disorder, Uncoupling protein",
author = "K. Hagym{\'a}si and Z. Tulassay",
year = "2006",
month = "1",
day = "22",
language = "Hungarian",
volume = "147",
pages = "107--113",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "3",

}

TY - JOUR

T1 - Az elhízás genetikája

AU - Hagymási, K.

AU - Tulassay, Z.

PY - 2006/1/22

Y1 - 2006/1/22

N2 - Obesity is a major health problem. It increases the risk of cardiovascular diseases, 2-type diabetes mellitus, cancers, and premature mortality. Apart from some monogenic forms, it's a polygenic disorder, the result of interaction of genes and environmental factors. Genetic variants of proteins taking part in the regulation of food intake or thermogenesis and tissue mediators produced by the adipose tissue are responsible the genetic components of obesity. Identification of the genetic background of the obesity will help to understand the exact molecular mechanism of the pathogenesis, make possible the prevention, as well as individual therapeutic interventions.

AB - Obesity is a major health problem. It increases the risk of cardiovascular diseases, 2-type diabetes mellitus, cancers, and premature mortality. Apart from some monogenic forms, it's a polygenic disorder, the result of interaction of genes and environmental factors. Genetic variants of proteins taking part in the regulation of food intake or thermogenesis and tissue mediators produced by the adipose tissue are responsible the genetic components of obesity. Identification of the genetic background of the obesity will help to understand the exact molecular mechanism of the pathogenesis, make possible the prevention, as well as individual therapeutic interventions.

KW - β3 adrenergic receptor

KW - Genetics

KW - Leptin

KW - Obesity

KW - Peroxisome-proliferator activated receptor-γ

KW - Polygenic disorder

KW - Uncoupling protein

UR - http://www.scopus.com/inward/record.url?scp=33645939209&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645939209&partnerID=8YFLogxK

M3 - Article

C2 - 16515029

AN - SCOPUS:33645939209

VL - 147

SP - 107

EP - 113

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 3

ER -