The fragmentation of actin by thrombin. Isolation and characterization of the split products

L. Muszbek, J. A. Gladner, K. Laki

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Thrombin, a limited protease, hydrolyzes three bonds in actin at Arg-28, Arg-39, and Lys-113, thereby producing two smaller peptides and two larger fragments. The location of the bonds split was identified in the amino acid sequence of actin by isolating the split products and carrying out amino acid analysis, and N- and C-terminal determinations.

Original languageEnglish
Pages (from-to)99-103
Number of pages5
JournalArchives of Biochemistry and Biophysics
Volume167
Issue number1
DOIs
Publication statusPublished - Mar 1975

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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