The First Synthesis of Azapterocarpans and Azaisoflavans: A Convenient Route to 3‐Aryl‐1,2,3,4‐Tetrahydroquinolines

Adrienne L. Tőkés, S. Antus

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The first synthesis of the 5,6,6a,11a‐tetrahydro[1]benzofuro[3,2‐c]quinolines (5‐azapterocarpans) 1–4 has been achieved by palladium‐catalyzed arylation of the appropriately substituted 1,2‐dihydroquinolines 15, 16. The 5‐azapterocarpans 3 and 4 have been transformed into the 3‐aryl‐1,2,3,4‐tetrahydroquinolines (azaisoflavans) 24 and 26, respectively, by reduction with Red‐Al®.

Original languageEnglish
Pages (from-to)911-915
Number of pages5
JournalLiebigs Annalen der Chemie
Volume1994
Issue number9
DOIs
Publication statusPublished - 1994

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Quinolines

Keywords

  • Azaisoflavans
  • Azapterocarpans
  • Heck‐type oxyarylation
  • Hydride shift
  • Quinolines

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The First Synthesis of Azapterocarpans and Azaisoflavans : A Convenient Route to 3‐Aryl‐1,2,3,4‐Tetrahydroquinolines. / Tőkés, Adrienne L.; Antus, S.

In: Liebigs Annalen der Chemie, Vol. 1994, No. 9, 1994, p. 911-915.

Research output: Contribution to journalArticle

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