The first synthesis of 7-alkylthio-2,2-dimethyl-2H-chromenes, the sulfur analogs of natural and synthetic precocenes

P. Sebok, T. Timar, T. Eszenyi, T. Patonay

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A new and expeditious synthesis of 7-alkylthio-2,2-dimethyl-2H-chromenes in good overall yield (59-72%), utilising the Newman-Kwart rearrangement of 7-(N,N-dimethylthiocarbamoyloxy)-2,2-dimethyl-4-chromanones as the key step, is described.

Original languageEnglish
Pages (from-to)837-840
Number of pages4
JournalSynthesis
Issue number8
Publication statusPublished - 1994

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Sulfur
5,7-dimethoxy-2-methyl-2H-benzopyran
4-chromanone

Keywords

  • 7-alkylthio-2,2-dimethyl-2H-chromenes
  • bioisostery
  • insect antijuvenile hormones
  • Newman-Kwar t rearrangement
  • precocenes

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

The first synthesis of 7-alkylthio-2,2-dimethyl-2H-chromenes, the sulfur analogs of natural and synthetic precocenes. / Sebok, P.; Timar, T.; Eszenyi, T.; Patonay, T.

In: Synthesis, No. 8, 1994, p. 837-840.

Research output: Contribution to journalArticle

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