Az elso sikeres kombinált szív- és veseátültetés Magyarországon

Translated title of the contribution: The first successful combined heart-kidney transplantation in Hungary

Tamás Benko, Fehérvári Imre, Kristóf Rácz, Orsolya Friedrich, Ildikó Gálfy, Szilárd Török, A. Remport, J. Járay, Elek Bodor, Zoltán Szabolcs

Research output: Contribution to journalArticle

Abstract

Combined heart-kidney transplantation has become a new therapeutic solution for patients with coexisting, irreversible heart and kidney failure. Though this combined approach has several theoretical advantages over sequential transplantation, it remains to be established whether it has a jeopardising impact on patient and graft outcome. The authors report their experience of the first successful combined heart-kidney transplantation in Hungary from a single donor and review the literature in order to clarify this issue. - Young male patient candidate for heart transplantation was suffering from concurrent end stage kidney disease. Donor was selected on the basis of weight and size matching, ABO compatibility and negative T-cell cross-match. The heart was grafted first, and after the hemodynamic stabilization kidney from the same donor was transplanted. The surgical procedure was uneventful. Heart and kidney function recovered quickly, and the patient is doing very well with good cardiac and renal function even a year following the double organ transplantation. The first Hungarian experience showed that combined heart-kidney transplantation is a therapeutic solution for patients with end stage heart and kidney failure. The lower rate of rejection compared to single heart or kidney transplantation, known from the literature as well, supports their current approach to immunosuppression.

Original languageHungarian
Pages (from-to)147-152
Number of pages6
JournalOrvosi Hetilap
Volume149
Issue number4
DOIs
Publication statusPublished - Jan 27 2008

Fingerprint

Hungary
Heart Transplantation
Kidney Transplantation
Tissue Donors
Kidney
Renal Insufficiency
Heart Failure
Organ Transplantation
Immunosuppression
Chronic Kidney Failure
Transplantation
Hemodynamics
T-Lymphocytes
Transplants
Weights and Measures
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Benko, T., Imre, F., Rácz, K., Friedrich, O., Gálfy, I., Török, S., ... Szabolcs, Z. (2008). Az elso sikeres kombinált szív- és veseátültetés Magyarországon. Orvosi Hetilap, 149(4), 147-152. https://doi.org/10.1556/OH.2008.28243

Az elso sikeres kombinált szív- és veseátültetés Magyarországon. / Benko, Tamás; Imre, Fehérvári; Rácz, Kristóf; Friedrich, Orsolya; Gálfy, Ildikó; Török, Szilárd; Remport, A.; Járay, J.; Bodor, Elek; Szabolcs, Zoltán.

In: Orvosi Hetilap, Vol. 149, No. 4, 27.01.2008, p. 147-152.

Research output: Contribution to journalArticle

Benko, T, Imre, F, Rácz, K, Friedrich, O, Gálfy, I, Török, S, Remport, A, Járay, J, Bodor, E & Szabolcs, Z 2008, 'Az elso sikeres kombinált szív- és veseátültetés Magyarországon', Orvosi Hetilap, vol. 149, no. 4, pp. 147-152. https://doi.org/10.1556/OH.2008.28243
Benko T, Imre F, Rácz K, Friedrich O, Gálfy I, Török S et al. Az elso sikeres kombinált szív- és veseátültetés Magyarországon. Orvosi Hetilap. 2008 Jan 27;149(4):147-152. https://doi.org/10.1556/OH.2008.28243
Benko, Tamás ; Imre, Fehérvári ; Rácz, Kristóf ; Friedrich, Orsolya ; Gálfy, Ildikó ; Török, Szilárd ; Remport, A. ; Járay, J. ; Bodor, Elek ; Szabolcs, Zoltán. / Az elso sikeres kombinált szív- és veseátültetés Magyarországon. In: Orvosi Hetilap. 2008 ; Vol. 149, No. 4. pp. 147-152.
@article{6ebfb323a7124bd5999e01a33601c0d7,
title = "Az elso sikeres kombin{\'a}lt sz{\'i}v- {\'e}s vese{\'a}t{\"u}ltet{\'e}s Magyarorsz{\'a}gon",
abstract = "Combined heart-kidney transplantation has become a new therapeutic solution for patients with coexisting, irreversible heart and kidney failure. Though this combined approach has several theoretical advantages over sequential transplantation, it remains to be established whether it has a jeopardising impact on patient and graft outcome. The authors report their experience of the first successful combined heart-kidney transplantation in Hungary from a single donor and review the literature in order to clarify this issue. - Young male patient candidate for heart transplantation was suffering from concurrent end stage kidney disease. Donor was selected on the basis of weight and size matching, ABO compatibility and negative T-cell cross-match. The heart was grafted first, and after the hemodynamic stabilization kidney from the same donor was transplanted. The surgical procedure was uneventful. Heart and kidney function recovered quickly, and the patient is doing very well with good cardiac and renal function even a year following the double organ transplantation. The first Hungarian experience showed that combined heart-kidney transplantation is a therapeutic solution for patients with end stage heart and kidney failure. The lower rate of rejection compared to single heart or kidney transplantation, known from the literature as well, supports their current approach to immunosuppression.",
keywords = "Chronic renal insufficiency, Combined transplantation, Heart failure, Heart transplantation, Kidney transplantation",
author = "Tam{\'a}s Benko and Feh{\'e}rv{\'a}ri Imre and Krist{\'o}f R{\'a}cz and Orsolya Friedrich and Ildik{\'o} G{\'a}lfy and Szil{\'a}rd T{\"o}r{\"o}k and A. Remport and J. J{\'a}ray and Elek Bodor and Zolt{\'a}n Szabolcs",
year = "2008",
month = "1",
day = "27",
doi = "10.1556/OH.2008.28243",
language = "Hungarian",
volume = "149",
pages = "147--152",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "4",

}

TY - JOUR

T1 - Az elso sikeres kombinált szív- és veseátültetés Magyarországon

AU - Benko, Tamás

AU - Imre, Fehérvári

AU - Rácz, Kristóf

AU - Friedrich, Orsolya

AU - Gálfy, Ildikó

AU - Török, Szilárd

AU - Remport, A.

AU - Járay, J.

AU - Bodor, Elek

AU - Szabolcs, Zoltán

PY - 2008/1/27

Y1 - 2008/1/27

N2 - Combined heart-kidney transplantation has become a new therapeutic solution for patients with coexisting, irreversible heart and kidney failure. Though this combined approach has several theoretical advantages over sequential transplantation, it remains to be established whether it has a jeopardising impact on patient and graft outcome. The authors report their experience of the first successful combined heart-kidney transplantation in Hungary from a single donor and review the literature in order to clarify this issue. - Young male patient candidate for heart transplantation was suffering from concurrent end stage kidney disease. Donor was selected on the basis of weight and size matching, ABO compatibility and negative T-cell cross-match. The heart was grafted first, and after the hemodynamic stabilization kidney from the same donor was transplanted. The surgical procedure was uneventful. Heart and kidney function recovered quickly, and the patient is doing very well with good cardiac and renal function even a year following the double organ transplantation. The first Hungarian experience showed that combined heart-kidney transplantation is a therapeutic solution for patients with end stage heart and kidney failure. The lower rate of rejection compared to single heart or kidney transplantation, known from the literature as well, supports their current approach to immunosuppression.

AB - Combined heart-kidney transplantation has become a new therapeutic solution for patients with coexisting, irreversible heart and kidney failure. Though this combined approach has several theoretical advantages over sequential transplantation, it remains to be established whether it has a jeopardising impact on patient and graft outcome. The authors report their experience of the first successful combined heart-kidney transplantation in Hungary from a single donor and review the literature in order to clarify this issue. - Young male patient candidate for heart transplantation was suffering from concurrent end stage kidney disease. Donor was selected on the basis of weight and size matching, ABO compatibility and negative T-cell cross-match. The heart was grafted first, and after the hemodynamic stabilization kidney from the same donor was transplanted. The surgical procedure was uneventful. Heart and kidney function recovered quickly, and the patient is doing very well with good cardiac and renal function even a year following the double organ transplantation. The first Hungarian experience showed that combined heart-kidney transplantation is a therapeutic solution for patients with end stage heart and kidney failure. The lower rate of rejection compared to single heart or kidney transplantation, known from the literature as well, supports their current approach to immunosuppression.

KW - Chronic renal insufficiency

KW - Combined transplantation

KW - Heart failure

KW - Heart transplantation

KW - Kidney transplantation

UR - http://www.scopus.com/inward/record.url?scp=39349091834&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39349091834&partnerID=8YFLogxK

U2 - 10.1556/OH.2008.28243

DO - 10.1556/OH.2008.28243

M3 - Article

C2 - 18201956

AN - SCOPUS:39349091834

VL - 149

SP - 147

EP - 152

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 4

ER -