The feasibility of liquid sample microanalysis using polydimethylsiloxane microfluidic chips with in-channel and in-port laser-induced breakdown spectroscopy detection

Anikó Metzinger, Andrea Nagy, A. Gáspár, Zsuzsanna Márton, Éva Kovács-Széles, Gábor Galbács

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This study describes the direct interfacing of polydimethylsiloxane (PDMS) microfluidic chips with laser-induced breakdown spectroscopy (LIBS) detection. The changes induced in the PDMS material by nanosecond laser ablation are briefly documented by using optical microscopy and scanning profilometry. The main part of the study focuses on the solution of technical and analytical problems of coupling single-pulse LIBS detection with PDMS microfluidic chips in order to assess the feasibility and performance of the concept of creating a lab-on-a-chip device with LIBS detection (LOC-LIBS). Multiple optical and sample presentation schemes including in-channel and in-port detection were tested, but it was found that LOC-LIBS is only viable and practical with in-port detection outside the chip. It was shown that LOC-LIBS in this configuration is capable of the trace speciation analysis of chromium using as little as 0.5 μL solution volume. The achieved absolute limit of detection was 2 ng.

Original languageEnglish
Pages (from-to)23-30
Number of pages8
JournalSpectrochimica Acta - Part B Atomic Spectroscopy
Volume126
DOIs
Publication statusPublished - Dec 1 2016

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Keywords

  • Chromium
  • Lab-on-a-chip (LOC)
  • Laser ablation
  • Laser-induced breakdown spectroscopy (LIBS)
  • Microfluidics
  • Polydimethylsiloxane (PDMS)

ASJC Scopus subject areas

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Spectroscopy

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