The facultative stem cell

A new star in Liver Pathology

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Although the unlimited capacity of hepatocytes to divide has been recently proven, more and more evidences support the existence of a primitive stem cell compartment in the liver. These cells probably do not participate in the usual maintenance of the liver mass, but they are activated in case of extensive hepatocyte injury. In vivo the oval cells show deep similarity to the primitive cells of the embryonic liver and seem to be the amplification compartment of the hepatic stem cells. A primitive epithelial cell population can be isolated from the normal liver and maintained in vitro. Studies of these two experimental systems provide most of the data about liver stem cells, which may become important for the clinical practice if we understand how their growth is regulated.

Original languageEnglish
Pages (from-to)23-26
Number of pages4
JournalPathology and Oncology Research
Volume1
Issue number1
DOIs
Publication statusPublished - Mar 1995

Fingerprint

Stem Cells
Pathology
Liver
Hepatocytes
Epithelial Cells
Maintenance
Wounds and Injuries
Growth
Population

Keywords

  • liver
  • oval cell carcinogenesis
  • stem cell

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oncology
  • Cancer Research

Cite this

The facultative stem cell : A new star in Liver Pathology. / Nagy, P.

In: Pathology and Oncology Research, Vol. 1, No. 1, 03.1995, p. 23-26.

Research output: Contribution to journalArticle

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