Introduction - The goal of the study was to evaluate the twenty transsexuals who visited the Genetic Counselling Clinic between 1980 and 1996, in the reflection of recent international literature. Patients, Method and Results - Of the 20, 12 were genetically female. Gonads and genitalia corresponded to their normal karyotypes. However, their sexual function indicated hypofunction in both sexes, the females had a nearly two years delay in the menarche and genital hypoplasia occurred in five genetical females, while sperm density was lower (22.8 ± 10.1 M/ml) compared to the national mean (40.3 ± 13.7 M/ml) in genetical males. Of the 12 genetic females, three had had a previous suicide attempt. No recurrence was found in their 23 sibs and 2 halfsibs. Conclusion - The data of these cases confirm the etiological role of the primary maldevelopment of cerebral-sex: the central nucleus of stria terminalis in the origin of male transsexualism.
|Translated title of the contribution||The evaluation of twenty transsexual cases|
|Number of pages||5|
|Journal||Lege Artis Medicinae|
|Publication status||Published - Oct 15 1997|
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