The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana

Mark R. Doyle, Seth J. Davis, Ruth M. Bastow, Harriet G. McWatters, L. Kozma-Bognár, Ferenc Nagy, Andrew J. Millar, Richard M. Amasino

Research output: Contribution to journalArticle

302 Citations (Scopus)

Abstract

Many plants use day length as an environmental cue to ensure proper timing of the switch from vegetative to reproductive growth. Day-length sensing involves an interaction between the relative length of day and night, and endogenous rhythms that are controlled by the plant circadian clock. Thus, plants with defects in circadian regulation cannot properly regulate the timing of the floral transition. Here we describe the gene EARLY FLOWERING 4 (ELF4), which is involved in photoperiod perception and circadian regulation. ELF4 promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. elf4 mutants show attenuated expression of CIRCADIAN CLOCK ASSOCIATED 1 (CCA1), a gene that is thought to function as a central oscillator component. In addition, elf4 plants transiently show output rhythms with highly variable period lengths before becoming arrhythmic. Mutations in elf4 result in early flowering in non-inductive photoperiods, which is probably caused by elevated amounts of CONSTANS (CO), a gene that promotes floral induction.

Original languageEnglish
Pages (from-to)74-77
Number of pages4
JournalNature
Volume419
Issue number6902
DOIs
Publication statusPublished - Sep 5 2002

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Circadian Rhythm
Arabidopsis
Photoperiod
Circadian Clocks
Genes
Cues
Mutation
Growth

ASJC Scopus subject areas

  • General

Cite this

Doyle, M. R., Davis, S. J., Bastow, R. M., McWatters, H. G., Kozma-Bognár, L., Nagy, F., ... Amasino, R. M. (2002). The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana. Nature, 419(6902), 74-77. https://doi.org/10.1038/nature00954

The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana. / Doyle, Mark R.; Davis, Seth J.; Bastow, Ruth M.; McWatters, Harriet G.; Kozma-Bognár, L.; Nagy, Ferenc; Millar, Andrew J.; Amasino, Richard M.

In: Nature, Vol. 419, No. 6902, 05.09.2002, p. 74-77.

Research output: Contribution to journalArticle

Doyle, MR, Davis, SJ, Bastow, RM, McWatters, HG, Kozma-Bognár, L, Nagy, F, Millar, AJ & Amasino, RM 2002, 'The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana', Nature, vol. 419, no. 6902, pp. 74-77. https://doi.org/10.1038/nature00954
Doyle, Mark R. ; Davis, Seth J. ; Bastow, Ruth M. ; McWatters, Harriet G. ; Kozma-Bognár, L. ; Nagy, Ferenc ; Millar, Andrew J. ; Amasino, Richard M. / The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana. In: Nature. 2002 ; Vol. 419, No. 6902. pp. 74-77.
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