The effects of oral Clonidine on the growth hormone level in acromegalic patients

L. Gáspár, T. Janáky, Zs Valkusz, F. A. László

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The effects of the noradrenergic agent Clonidine on GH secretion of the adenohypophysis were studied in 10 healthy volunteers and 11 acromegalic patients. Orally administered Clonidine led to a considerable serum human growth hormone (GH) level increase in the healthy individuals. In the acromegalic patients the Clonidine resulted in a slight, but not significant GH increase. These results support the findings that the mechanism of noradrenergic regulation of serum GH secretion is impaired in acromegaly.

Original languageEnglish
Pages (from-to)327-329
Number of pages3
JournalJournal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology
Volume7
Issue number4
DOIs
Publication statusPublished - Aug 1984

Keywords

  • Clonidine
  • acromegaly
  • growth hormone level
  • noradrenergic regulation

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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