The effects of Oradexone and Ambroxol pretreatment on the oxidative sensitivity of the red blood cells in preterm infants

Z. Novák, Sz I. Varga, L. Kovács, A. Pál, L. Pataki, B. Matkovics

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The antioxidant enzyme activities and lipid peroxidation in the red blood cells of cord blood were investigated and compared at different gestation times in preterm and full-term neonates, with and without pretreatment of the pregnant mothers with Oradexone (Dexamethasone) or Ambroxol. Administration of the two drugs not only stimulated the lung surfactant system, but also exerted favourable effects on the antioxidant enzyme activities while the lipid peroxidation was decreased.

Original languageEnglish
Pages (from-to)241-245
Number of pages5
JournalClinica Chimica Acta
Volume182
Issue number3
DOIs
Publication statusPublished - Jul 14 1989

Fingerprint

Ambroxol
Enzyme activity
Premature Infants
Lipid Peroxidation
Blood
Antioxidants
Erythrocytes
Cells
Lipids
Enzymes
Fetal Blood
Surface-Active Agents
Dexamethasone
Mothers
Newborn Infant
Pregnancy
Lung
Pharmaceutical Preparations

Keywords

  • Antioxidant enzyme
  • Lipid peroxidation comparison
  • Pretreatment with Oradexone and Ambroxol
  • Red blood cell

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry

Cite this

The effects of Oradexone and Ambroxol pretreatment on the oxidative sensitivity of the red blood cells in preterm infants. / Novák, Z.; Varga, Sz I.; Kovács, L.; Pál, A.; Pataki, L.; Matkovics, B.

In: Clinica Chimica Acta, Vol. 182, No. 3, 14.07.1989, p. 241-245.

Research output: Contribution to journalArticle

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