The effect on escherichia coli B of "radioprotectors" produced by fermentation

F. Hernádi, I. Békési, Zs Nagy, A. Jeney, T. Vályi-Nagy

Research output: Contribution to journalArticle

Abstract

1. The radioprotective activity of several hundreds of fermentation liquids have been examined by methods described in our previous reports. 2. Out of the tested fermentation liquids, good protective ability was rendered-mainly after acid hydrolysis-by the fermentation liquid of Penicillium notatum strain which is applied also in industry. 3. The agent, when it was produced, proved to be d-Penicillamine. 4. The radioprotective activity of d-Penicillamine as well as its ability to reduce the toxicity of nitrogen mustard have been compared with the effect of other wellknown radioprotectors, on an equimolar basis. 5. It was found that its protective ability for E. coli B against both X-ray and nitrogen mustard is about the same degree as that of cysteine. 6. From the results, theoretical and practical conclusions have been drawn.

Original languageEnglish
Pages (from-to)228-232
Number of pages5
JournalArchiv für Mikrobiologie
Volume44
Issue number3
DOIs
Publication statusPublished - Sep 1962

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Fermentation
Escherichia coli
Mechlorethamine
Penicillamine
Liquids
Penicillium chrysogenum
Cysteine
Toxicity
Hydrolysis
Industry
Thermodynamic properties
X-Rays
X rays
Acids

ASJC Scopus subject areas

  • Microbiology
  • Medicine(all)

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The effect on escherichia coli B of "radioprotectors" produced by fermentation. / Hernádi, F.; Békési, I.; Nagy, Zs; Jeney, A.; Vályi-Nagy, T.

In: Archiv für Mikrobiologie, Vol. 44, No. 3, 09.1962, p. 228-232.

Research output: Contribution to journalArticle

Hernádi, F. ; Békési, I. ; Nagy, Zs ; Jeney, A. ; Vályi-Nagy, T. / The effect on escherichia coli B of "radioprotectors" produced by fermentation. In: Archiv für Mikrobiologie. 1962 ; Vol. 44, No. 3. pp. 228-232.
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