Platelet-rich plasma (thrombocyta-koncentrátum) hatása a csontképzõdésre oszteokonduktív csontpótlóval (beta-trikalcium-foszfát) történõ együttes alkalmazáskor Beagle kutyákon.

Translated title of the contribution: The effect of platelet-rich plasma on new bone formation by augmentation with osseoconductive bone substitute material in beagle dogs

Norbert Velich, Katalin Kovács, Tamás Huszár, Gábor Semjén, J. Reiczigel, György Szabó, Z. Suba

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Animal experiments were carried out with osseoconductive bone substitute beta-tricalcium phosphate (beta-TCP), with the aim of assessing the effect of the growth factors synthesized by platelets on the speed of beta-TCP incorporation and on the quality of newly formed bone. The question arises whether the results attained with this synthetic material approach are comparable to those attained with autologous bone. Defects in the mandibles of beagle dogs were filled with beta-TCP or with the mixture of beta-TCP and platelet rich plasma (PRP) obtained from autologous blood. The quality of the newly formed bone and the effect of PRP were studied by histologic and histomorphometric methods. On the 6th week, bone formation seemed to be more effective when PRP was applied in comparison with beta-TCP alone, but the difference was not significant. On the 12th week bone formation was significantly greater. The results demonstrate that the use of PRP accelerates the remodelling of the synthetic bone-substitute material beta-TCP.

Original languageHungarian
Pages (from-to)23-27
Number of pages5
JournalFogorvosi szemle
Volume97
Issue number1
Publication statusPublished - 2004

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Bone Substitutes
Platelet-Rich Plasma
Osteogenesis
Dogs
Bone and Bones
Mandible
beta-tricalcium phosphate
Intercellular Signaling Peptides and Proteins
Blood Platelets

Cite this

Platelet-rich plasma (thrombocyta-koncentrátum) hatása a csontképzõdésre oszteokonduktív csontpótlóval (beta-trikalcium-foszfát) történõ együttes alkalmazáskor Beagle kutyákon. / Velich, Norbert; Kovács, Katalin; Huszár, Tamás; Semjén, Gábor; Reiczigel, J.; Szabó, György; Suba, Z.

In: Fogorvosi szemle, Vol. 97, No. 1, 2004, p. 23-27.

Research output: Contribution to journalArticle

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