PHENOBARBITAL ES NOR ANDROSTENOLON PHENYLPROPIONAT HATASA THIOACETAMID CIRRHOSISOS PATKANYOK HEXOBARBITAL ALVASI IDEJERE

Translated title of the contribution: The effect of phenobarbital and norandrostenolone phenylpropionate on the duration of hexobarbital anesthesia in rats with thioacetamide induced cirrhosis

A. Pap, G. Marosi, F. Szarvas

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In rats with experimental hepatic cirrhosis produced by 8 mth administration of thioacetamide the duration of hexobarbital anaesthesia was examined. One week after discontinuance of the poison the sleeping time was prolonged, corresponding to the reduced metabolism of hexobarbital. By premedication of phenobarbital sodium and norandrostenolone phenylpropionate the sleeping time of the cirrhotic animals was considerably shortened. This is attributed to microsomal enzyme induction occurring in the preserved cells still capable of reaction.

Translated title of the contributionThe effect of phenobarbital and norandrostenolone phenylpropionate on the duration of hexobarbital anesthesia in rats with thioacetamide induced cirrhosis
Original languageHungarian
Pages (from-to)537-540
Number of pages4
JournalKiserletes Orvostudomany
Volume25
Issue number5
Publication statusPublished - Jan 1 1973

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'The effect of phenobarbital and norandrostenolone phenylpropionate on the duration of hexobarbital anesthesia in rats with thioacetamide induced cirrhosis'. Together they form a unique fingerprint.

  • Cite this