The main psychoactive component of marihuana, delta-9 tetrahydrocannabinol (THC), was administered intraperitoneally to pregnant rats. From day one of pregnancy up to the last day 1ug/kg b.w./day of THC was injected. The control group received physiological saline. Out of the 34 THC injected pregnant rats only 7 (21%) had deliveries in time. THC resulted in prolongation of gestation by 1-4 days (avr. 2 days) in 79% of pregnancies. In the latter cases there were more han 40% stillbirths, approx. 25% macerated foetuses. 25-30% were the victims of mother's cannibalism. The results emphasize the significance of marihuana consumption during pregnancy, i.e. fetal development.
|Number of pages||5|
|Publication status||Published - Jan 1 1988|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrine and Autonomic Systems
- Clinical Neurology
- Psychiatry and Mental health