The effect of increasing glucose in CPD on the quality of stored blood

E. Hegedus, V. Harsanyi, S. R. Hollan

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Abstract

Changes in quality of blood units containing one and a half or double amounts of glucose, stored at +4°C for three weeks were analyzed. An experimental preservative containing glucose and fructose (1:1) was also used. No other additives (purine or purine-nucleoside) were applied. A standard CPD preservative of the Nationl Inst. of Haematology and Blood Transfusion was used as a control. The pH, plasma free haemoglobin K+ content, red blood cell (RBC) r162w2 =improved ATP and 2,3-DPG content, and RBC fragility index were determined in each sample. The increase of glucose concentration and the addition of fructose had a beneficial effect on blood pH, and on plasma free haemoglobin and K+ concentration. 150% glucose imrpved the 2,3-DPG maintenance in stored blood.

Original languageEnglish
Pages (from-to)928-933
Number of pages6
JournalFolia Haematologica
Volume107
Issue number6
Publication statusPublished - Dec 1 1980

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ASJC Scopus subject areas

  • Hematology

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