The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain.

M. J. Brownstein, A. Arimura, R. Fernandez-Durango, A. V. Schally, M. Palkóvits, J. S. Kizer

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Somatostatin-like activity (SLA) was determined by radioimmunoassay in several brain regions of animals which had either undergone complete deafferentation of the medial basal hypothalamus or a sham-operation. Surgical isolation of the medial basal hypothalamus caused this region to lose most of its SLA, but did not affect activity elsewhere. Similarly, partial (frontal) deafferentation of the medial basal hypothalamus resulted in a substantial decrease in SLA there.

Original languageEnglish
Pages (from-to)246-249
Number of pages4
JournalEndocrinology
Volume100
Issue number1
Publication statusPublished - Jan 1977

Fingerprint

Middle Hypothalamus
Somatostatin
Brain
Radioimmunoassay

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Brownstein, M. J., Arimura, A., Fernandez-Durango, R., Schally, A. V., Palkóvits, M., & Kizer, J. S. (1977). The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain. Endocrinology, 100(1), 246-249.

The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain. / Brownstein, M. J.; Arimura, A.; Fernandez-Durango, R.; Schally, A. V.; Palkóvits, M.; Kizer, J. S.

In: Endocrinology, Vol. 100, No. 1, 01.1977, p. 246-249.

Research output: Contribution to journalArticle

Brownstein, MJ, Arimura, A, Fernandez-Durango, R, Schally, AV, Palkóvits, M & Kizer, JS 1977, 'The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain.', Endocrinology, vol. 100, no. 1, pp. 246-249.
Brownstein MJ, Arimura A, Fernandez-Durango R, Schally AV, Palkóvits M, Kizer JS. The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain. Endocrinology. 1977 Jan;100(1):246-249.
Brownstein, M. J. ; Arimura, A. ; Fernandez-Durango, R. ; Schally, A. V. ; Palkóvits, M. ; Kizer, J. S. / The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain. In: Endocrinology. 1977 ; Vol. 100, No. 1. pp. 246-249.
@article{3f441e7696c0438a85100de44d81e31a,
title = "The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain.",
abstract = "Somatostatin-like activity (SLA) was determined by radioimmunoassay in several brain regions of animals which had either undergone complete deafferentation of the medial basal hypothalamus or a sham-operation. Surgical isolation of the medial basal hypothalamus caused this region to lose most of its SLA, but did not affect activity elsewhere. Similarly, partial (frontal) deafferentation of the medial basal hypothalamus resulted in a substantial decrease in SLA there.",
author = "Brownstein, {M. J.} and A. Arimura and R. Fernandez-Durango and Schally, {A. V.} and M. Palk{\'o}vits and Kizer, {J. S.}",
year = "1977",
month = "1",
language = "English",
volume = "100",
pages = "246--249",
journal = "Endocrinology",
issn = "0013-7227",
publisher = "The Endocrine Society",
number = "1",

}

TY - JOUR

T1 - The effect of hypothalamic deafferentation on somatostatin-like activity in the rat brain.

AU - Brownstein, M. J.

AU - Arimura, A.

AU - Fernandez-Durango, R.

AU - Schally, A. V.

AU - Palkóvits, M.

AU - Kizer, J. S.

PY - 1977/1

Y1 - 1977/1

N2 - Somatostatin-like activity (SLA) was determined by radioimmunoassay in several brain regions of animals which had either undergone complete deafferentation of the medial basal hypothalamus or a sham-operation. Surgical isolation of the medial basal hypothalamus caused this region to lose most of its SLA, but did not affect activity elsewhere. Similarly, partial (frontal) deafferentation of the medial basal hypothalamus resulted in a substantial decrease in SLA there.

AB - Somatostatin-like activity (SLA) was determined by radioimmunoassay in several brain regions of animals which had either undergone complete deafferentation of the medial basal hypothalamus or a sham-operation. Surgical isolation of the medial basal hypothalamus caused this region to lose most of its SLA, but did not affect activity elsewhere. Similarly, partial (frontal) deafferentation of the medial basal hypothalamus resulted in a substantial decrease in SLA there.

UR - http://www.scopus.com/inward/record.url?scp=0017421230&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017421230&partnerID=8YFLogxK

M3 - Article

C2 - 830542

AN - SCOPUS:0017421230

VL - 100

SP - 246

EP - 249

JO - Endocrinology

JF - Endocrinology

SN - 0013-7227

IS - 1

ER -