Lokális ho- es mechanikai stressz (masszázs) stimuláció hatása az emberi kevert nyál molekuláris chaperon (Hsp70) koncentrációjára. Elozetes vizsgálatok.

Translated title of the contribution: The effect of heat stimulation and mechanical stress (massage) of salivary glands on the secretory parameters of salivary Hsp70. A pilot study

László Féjerdy, Zsuzsanna Tóth, Borbála Kaán, Károly Fábián Tibor, Péter Csermely, Pál Fejérdy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The presence of Hsp70 in human whole saliva was demonstrated in the authors' previous study. In the recent study the authors investigated, whether repeated, short-term heat and mechanical stimulation of the salivary glands can specifically modify the salivary Hsp70 concentration in the human whole saliva. Some other basic secretory parameters, like salivary secretion rate, total protein concentration and amylase activity of the whole saliva were also measured. Both kind of stimulation increased the secretory rate significantly (p < or = 0.05), during stimulation, but it decreased to control level in resting phases. Hsp70 concentration increased after the first stimulation in the case of mechanical stress and after the second stimulation in the case of heat stimulation. In contrast, a significant (p < or = 0.05) confluent increase of total protein concentration and amylase activity occurred after the first stimulation in the case of heat stimulation and after the second stimulation in the case of mechanical stress. Further investigations are needed to evaluate the durability and clinical importance of salivary changes following local heat and massage stimulation.

Original languageHungarian
Pages (from-to)204-210
Number of pages7
JournalFogorvosi szemle
Volume97
Issue number5
Publication statusPublished - Oct 2004

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ASJC Scopus subject areas

  • Medicine(all)

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