DIE WIRKUNG DER WAHREND DER GRAVIDITAT DURCHGEFUHRTEN GLUCOKORTIKOIDBEHANDLUNG AUF DIE NEBENNIERENFUNKTION DER NEUGEBORENEN RATTEN

Translated title of the contribution: The effect of glucocorticoid treatment during pregnancy on adrenal function in newborn rats

I. Szabó, J. Bodis, I. Drozgyik

Research output: Contribution to journalArticle

Abstract

The authors examined the effect of prednisolone-salium succinate administered on the 17th or 18th day of pregnancy on the adrenal function of newborn rats. They found that in doses of 1.0 or 2.0 mg/kg it does not affect physiological development or, respectively, the extent of the circadian rhythm or the stress response. However, the adrenal function of newborn animals was significantly inhibited by 30.0 mg/kg as regards its adaptability to extra-uterine life. The authors point out the importance of investigations to determine the adrenal function of newborns following steroid therapy to prevent RDS.

Original languageGerman
Pages (from-to)27-30
Number of pages4
JournalZeitschrift fur Geburtshilfe und Perinatologie
Volume186
Issue number1
Publication statusPublished - 1982

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Newborn Animals
Succinic Acid
Circadian Rhythm
Prednisolone
Glucocorticoids
Steroids
Pregnancy
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health

Cite this

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