The effect of erythropoietin on platelet function in uraemic children on haemodialysis

S. Túri, Jozsef Soos, Csilla Torday, C. Bereczki, Zoltan Havass

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The effect of 1-year erythropoietin (rHu-EPO) treatment on the bleeding time, platelet aggregation, ATP and thromboxane B2 (TXB2) release, cyclic AMP (cAMP) concentration and platelet surface positive charge were studied in 8 haemodialysed children with chronic uraemia and 8 controls. The pre-dialysis haematocrit (Hct) was 0.21+0.01 before and 0.36+0.01 following 1 year of rHu-EPO therapy. At the end of this period the pre-dialysis bleeding time became normal (P2 production (P2 production and a decrease in platelet cAMP concentration was observed following bicarbonate haemodialysis (BHD) (P2 production (r=0.68, P

Original languageEnglish
Pages (from-to)727-732
Number of pages6
JournalPediatric Nephrology
Volume8
Issue number6
DOIs
Publication statusPublished - Dec 1994

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Bleeding Time
Erythropoietin
Cyclic AMP
Renal Dialysis
Dialysis
Blood Platelets
Thromboxane B2
Uremia
Bicarbonates
Platelet Aggregation
Hematocrit
Adenosine Triphosphate
Therapeutics

Keywords

  • Erythropoietin
  • Haemodialysis
  • Platelet function
  • Uraemic children

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

Cite this

The effect of erythropoietin on platelet function in uraemic children on haemodialysis. / Túri, S.; Soos, Jozsef; Torday, Csilla; Bereczki, C.; Havass, Zoltan.

In: Pediatric Nephrology, Vol. 8, No. 6, 12.1994, p. 727-732.

Research output: Contribution to journalArticle

Túri, S. ; Soos, Jozsef ; Torday, Csilla ; Bereczki, C. ; Havass, Zoltan. / The effect of erythropoietin on platelet function in uraemic children on haemodialysis. In: Pediatric Nephrology. 1994 ; Vol. 8, No. 6. pp. 727-732.
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