The effect of ceramic fibers on the immune system.

Jana Tulinská, Miroslava Kuricová, Aurelia Lisková, Zuzana Kováciková, E. Tátrai

Research output: Contribution to journalArticle

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Abstract

Male Sprague-Dawley rats were treated by intratracheal instillation with 1 mg/animal of refractory ceramic fibers. Intratracheal exposure to ceramic fibers led to significant changes of immune response. Results of proliferative activity of spleen lymphocytes showed significantly decreased proliferative activity of T-cells in response to mitogens phytohemagglutinin and concanavalin A in animals given ceramic fibers in comparison with control rats. Similarly, T-dependent B-cell response to pokeweed mitogen was significantly suppressed. Spontaneous proliferative activity of lymphocytes in non-stimulated spleen cell cultures did not differ in exposed and control rats. No significant changes were found among groups in percentage of phagocytic blood polymorphonuclear leukocytes and percentage of cells with respiratory burst.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalBiomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Volume149
Issue number2
Publication statusPublished - Dec 2005

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Ceramic fibers
Immune system
Ceramics
Immune System
Rat control
Lymphocytes
Spleen
Pokeweed Mitogens
Animals
Respiratory Burst
Phytohemagglutinins
Concanavalin A
Mitogens
Sprague Dawley Rats
T-cells
Neutrophils
B-Lymphocytes
Cell Culture Techniques
Cell culture
T-Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The effect of ceramic fibers on the immune system. / Tulinská, Jana; Kuricová, Miroslava; Lisková, Aurelia; Kováciková, Zuzana; Tátrai, E.

In: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, Vol. 149, No. 2, 12.2005, p. 397-399.

Research output: Contribution to journalArticle

Tulinská, Jana ; Kuricová, Miroslava ; Lisková, Aurelia ; Kováciková, Zuzana ; Tátrai, E. / The effect of ceramic fibers on the immune system. In: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia. 2005 ; Vol. 149, No. 2. pp. 397-399.
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