The effect of calcium entry blocker S-emopamil on cerebrocortical metabolism and blood flow changes evoked by graded hypotension.

A. G. Kovách, L. T. Nguyen, L. Pék, L. Dezsi, Z. S. Lohinai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Our studies demonstrate that in the explanation of the protective effect of the calcium antagonist (S)-emopamil the possibility of beneficial metabolic causes (lower O2 consumption) must also be considered beside of blood flow increasing effects. It is suggested that (S)-emopamil may be a useful drug for the treatment of cerebro-ischemic disorders.

Original languageEnglish
Pages (from-to)461-470
Number of pages10
JournalAdvances in experimental medicine and biology
Volume248
DOIs
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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