The publication presents the distribution and elimination of fumonisins after oral administration of 50 mg FB1, 20 mg FB2 and 5 mg FB3/animal/day for 22 days in weaned barrows. Lung, heart, liver, kidney, spleen, brain, serum, bile, muscle, fat, urine and faeces samples were collected and content of fumonisins was analysed by LC-MS. The highest FB 1 concentrations were found in the liver (99.4 ng/g ±37.5) and kidneys (30.6 ng/g ±10.1), while the highest average amount of FB 2 was found in the liver (1.4 ng/g ±2.3) and the fat (2.6 ng/g ±4.8) samples. Comparing the FB1/FB2 ratio in different organs (19/1) it was found that the ratio in the abdominal and subcutaneous fat samples (4/1) was markedly different from those in all other tissues, namely the relative proportion of FB2 was higher in latter cases. 13% of the total quantity of FB1 taken up during 5 days was excreted unchanged with faeces and urine. In average, in the urine and in the faeces FB1 was detected in 9- and 14-fold quantities, as compared to FB2.
|Translated title of the contribution||The distribution and elimination of fumonisins after oral administration of Fusarium verticillioides fungal culture|
|Number of pages||9|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 12 2006|
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