A herpesencephalitis diagnosztikájáról egy esetismertetés kapcsán

Translated title of the contribution: The diagnosis of herpesencephalitis a case-based update

Tamás Csonka, Rita Szepesi, László Bidiga, M. Péter, A. Klekner, Gábor Hutóczky, L. Csiba, G. Méhes, T. Hortobágyi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Herpes simplex virus encephalitis (HSVE) is a rare and life-threatening infection. The clinical signs are diverse and often misleading regarding the aetiology. However, focal seizure with fewer and typical CT/MRI finding should always raise the possibility of HSVE as early diagnosis and antiviral therapy is crucial. Before the advent of molecular techniques and high-tech imaging histological examination from multiple brain biopsies were often necessary. Although nowadays PCR and other molecular methods may provide an aetiological diagnosis some cases need neuropathological verification. Due to the high IgG seropositivity rate in the population the plasma IgG titer is not diagnostic and elevation of its plasma level requires several weeks. We report the case of a 25-years old male patient who initially presented with epileptic fits. There was no final diagnosis and causal treatment in the district general hospital. The patient was admitted to our institution in comatose state on day 9; the initiated diagnostic tests and therapy could not save the patient who died next day. The autopsy and subsequent neuropathological examination revealed HSVE. We present a flowchart on diagnostic work-up and special techniques to aid diagnosis in suspected viral encephalitis.

Original languageHungarian
Pages (from-to)337-342
Number of pages6
JournalIdeggyógyászati szemle
Volume66
Issue number9-10
Publication statusPublished - Sep 30 2013

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Herpes Simplex Encephalitis
Simplexvirus
Immunoglobulin G
Viral Encephalitis
Software Design
District Hospitals
Coma
Routine Diagnostic Tests
General Hospitals
Antiviral Agents
Early Diagnosis
Autopsy
Seizures
Therapeutics
Biopsy
Polymerase Chain Reaction
Brain
Infection
Population

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

A herpesencephalitis diagnosztikájáról egy esetismertetés kapcsán. / Csonka, Tamás; Szepesi, Rita; Bidiga, László; Péter, M.; Klekner, A.; Hutóczky, Gábor; Csiba, L.; Méhes, G.; Hortobágyi, T.

In: Ideggyógyászati szemle, Vol. 66, No. 9-10, 30.09.2013, p. 337-342.

Research output: Contribution to journalArticle

Csonka T, Szepesi R, Bidiga L, Péter M, Klekner A, Hutóczky G et al. A herpesencephalitis diagnosztikájáról egy esetismertetés kapcsán. Ideggyógyászati szemle. 2013 Sep 30;66(9-10):337-342.
Csonka, Tamás ; Szepesi, Rita ; Bidiga, László ; Péter, M. ; Klekner, A. ; Hutóczky, Gábor ; Csiba, L. ; Méhes, G. ; Hortobágyi, T. / A herpesencephalitis diagnosztikájáról egy esetismertetés kapcsán. In: Ideggyógyászati szemle. 2013 ; Vol. 66, No. 9-10. pp. 337-342.
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