The diagnosis and treatment of the nonimmune hydrops fetalis.

A. Pál, U. Gembruch, R. Bald, M. Hansmann

Research output: Contribution to journalArticle

Abstract

Fetal hydrops is associated with two distinct pathophysiologic situations. The isoimmune hydrops fetalis is a well understood disorder, and as the result of medical advances and prophylactic therapy its frequency is diminishing. The nonimmune hydrops fetalis is a poorly understood disease with a bad prognosis. The two disorders can be differentiated with the indirect Coombs test. In both cases the ultrasound examination plays an important role in the diagnosis, prognosis and management. Examination of the fetal blood sample gives recently a possibility to approach the disease. In NIHF the examination of fetal blood sample would give a relatively quick and effective diagnosis but its value for the treatment is limited. Although with the present technology it is impossible to diagnose all cases of NIHF, the early recognizing, the careful and step by step investigation, the active perinatologic management mostly can show the etiology and can help the perinatal team at the treatment of the disease.

Original languageEnglish
Pages (from-to)169-186
Number of pages18
JournalActa Paediatrica Hungarica
Volume31
Issue number2
Publication statusPublished - 1991

Fingerprint

Hydrops Fetalis
Fetal Blood
Coombs Test
Technology
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pál, A., Gembruch, U., Bald, R., & Hansmann, M. (1991). The diagnosis and treatment of the nonimmune hydrops fetalis. Acta Paediatrica Hungarica, 31(2), 169-186.

The diagnosis and treatment of the nonimmune hydrops fetalis. / Pál, A.; Gembruch, U.; Bald, R.; Hansmann, M.

In: Acta Paediatrica Hungarica, Vol. 31, No. 2, 1991, p. 169-186.

Research output: Contribution to journalArticle

Pál, A, Gembruch, U, Bald, R & Hansmann, M 1991, 'The diagnosis and treatment of the nonimmune hydrops fetalis.', Acta Paediatrica Hungarica, vol. 31, no. 2, pp. 169-186.
Pál, A. ; Gembruch, U. ; Bald, R. ; Hansmann, M. / The diagnosis and treatment of the nonimmune hydrops fetalis. In: Acta Paediatrica Hungarica. 1991 ; Vol. 31, No. 2. pp. 169-186.
@article{f644fc89814c417cbaf1ebbdc0d3b2ff,
title = "The diagnosis and treatment of the nonimmune hydrops fetalis.",
abstract = "Fetal hydrops is associated with two distinct pathophysiologic situations. The isoimmune hydrops fetalis is a well understood disorder, and as the result of medical advances and prophylactic therapy its frequency is diminishing. The nonimmune hydrops fetalis is a poorly understood disease with a bad prognosis. The two disorders can be differentiated with the indirect Coombs test. In both cases the ultrasound examination plays an important role in the diagnosis, prognosis and management. Examination of the fetal blood sample gives recently a possibility to approach the disease. In NIHF the examination of fetal blood sample would give a relatively quick and effective diagnosis but its value for the treatment is limited. Although with the present technology it is impossible to diagnose all cases of NIHF, the early recognizing, the careful and step by step investigation, the active perinatologic management mostly can show the etiology and can help the perinatal team at the treatment of the disease.",
author = "A. P{\'a}l and U. Gembruch and R. Bald and M. Hansmann",
year = "1991",
language = "English",
volume = "31",
pages = "169--186",
journal = "European Journal of Pediatrics",
issn = "0340-6199",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - The diagnosis and treatment of the nonimmune hydrops fetalis.

AU - Pál, A.

AU - Gembruch, U.

AU - Bald, R.

AU - Hansmann, M.

PY - 1991

Y1 - 1991

N2 - Fetal hydrops is associated with two distinct pathophysiologic situations. The isoimmune hydrops fetalis is a well understood disorder, and as the result of medical advances and prophylactic therapy its frequency is diminishing. The nonimmune hydrops fetalis is a poorly understood disease with a bad prognosis. The two disorders can be differentiated with the indirect Coombs test. In both cases the ultrasound examination plays an important role in the diagnosis, prognosis and management. Examination of the fetal blood sample gives recently a possibility to approach the disease. In NIHF the examination of fetal blood sample would give a relatively quick and effective diagnosis but its value for the treatment is limited. Although with the present technology it is impossible to diagnose all cases of NIHF, the early recognizing, the careful and step by step investigation, the active perinatologic management mostly can show the etiology and can help the perinatal team at the treatment of the disease.

AB - Fetal hydrops is associated with two distinct pathophysiologic situations. The isoimmune hydrops fetalis is a well understood disorder, and as the result of medical advances and prophylactic therapy its frequency is diminishing. The nonimmune hydrops fetalis is a poorly understood disease with a bad prognosis. The two disorders can be differentiated with the indirect Coombs test. In both cases the ultrasound examination plays an important role in the diagnosis, prognosis and management. Examination of the fetal blood sample gives recently a possibility to approach the disease. In NIHF the examination of fetal blood sample would give a relatively quick and effective diagnosis but its value for the treatment is limited. Although with the present technology it is impossible to diagnose all cases of NIHF, the early recognizing, the careful and step by step investigation, the active perinatologic management mostly can show the etiology and can help the perinatal team at the treatment of the disease.

UR - http://www.scopus.com/inward/record.url?scp=0026086594&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026086594&partnerID=8YFLogxK

M3 - Article

C2 - 1867885

AN - SCOPUS:0026086594

VL - 31

SP - 169

EP - 186

JO - European Journal of Pediatrics

JF - European Journal of Pediatrics

SN - 0340-6199

IS - 2

ER -