Az inzulinkezelés fejlödése az inzulin felfedezésétöl az analóg inzulinokig

Translated title of the contribution: The development of insulin treatment from discovery of insulin to analogue preparations

Miklós Káplár, György Paragh

Research output: Contribution to journalArticle

Abstract

The discovery of insulin was a milestone in the treatment of diabetes mellitus. Animalderived (porcine and cattle) insulins available at the beginning were later replaced by human insulins. Recently, analogue insulins are the most widespreadly used. Besides the increase in the quantity and improvement in the quality of the insulin products, the growth of the treatment regimes is apparent, as well. That varies from the once-given daily basal insulin treatment added to oral antidiabetic drugs to intensified insulin therapy, administering insulin 4-5 times daily. Considering the benefits proved by previous basic and clinical studies, the authors summarize the most important properties of the commonly used insulin treatment regimes in this review. They also briefly outline the important aspects of the patient-centered personalized therapy and the connection between insulin therapy and carcinogenesis.

Original languageHungarian
Pages (from-to)519-524
Number of pages6
JournalLege Artis Medicinae
Volume21
Issue number8-9
Publication statusPublished - Aug 1 2011

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ASJC Scopus subject areas

  • Medicine(all)

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