1. 1. The dependence of pump-induced hyperpolarization of the membrane on the quantity of sodium ions injected into the cell and the tonicity of the surrounding medium was studied. 2. 2. The quantity of injected sodium ions necessary for saturation of the mechanism of active electrogenic transport varied from cell to cell ranging from 0.10 to 0.25 and from 0.18 to 0.37 nM in hypertonic and hypotonic solutions, respectively. 3. 3. At a low dose of sodium injection, much lower than the saturation region, the pump-induced hyperpolarization of the membrane was smaller in hypotonic solutions in comparison with that in hypertonic solutions. 4. 4. However, at a high dose of injected sodium ions when the mechanism of active electrogenic transport was saturated, the pump-induced hyperpolarization became larger in hypotonic solutions compared to that in hypertonic solutions.
|Number of pages||5|
|Journal||Comparative Biochemistry and Physiology -- Part A: Physiology|
|Publication status||Published - 1984|
ASJC Scopus subject areas