The course of thyrotropin-releasing hormone fibers to the median eminence in rats

Mikl#x F3;S Palkovits, R. L. Eskay, Michael J. Brownstein

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The topographical distribution of fibers containing TRH that run to the median eminence has been investigated by RIA of TRH after hypothalamic surgical transections in rats. Anterolateral or lateral cuts bilaterally transecting fibers at the caudal edge of the optic chiasm (lateral retrochiasmatic area) diminish TRH levels in the median eminence by 95% and 73%, respectively. Paramedian cuts are ineffective. These results suggest that TRH fibers reach the medial basal hypothalamus from an anterolateral direction just as several other classes of peptide containing fibers do.

Original languageEnglish
Pages (from-to)1526-1528
Number of pages3
JournalEndocrinology
Volume110
Issue number5
DOIs
Publication statusPublished - May 1982

ASJC Scopus subject areas

  • Endocrinology

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